Aim. To assess the morphological changes of rectal wall after the exposure to 970 and 1560 nm wavelength laser radiation and to choose the optimal wavelength for laser cauterization of hemorrhoids. Methods. Experiments to assess the effect of the exposure to 970 and 1560 nm wavelength laser radiation on rectal tissues were performed. Laser cauterization was modeled on white rats (two groups 18 animals each). «Mediola-Compact» semiconductor laser (manufactured by «Fotek» ldt, Belarus) was used. Animals of the first group were exposed to laser radiation with wavelength of 970 nm, 1560 nm wavelength was used in the second group. Animals were withdrawn from the experiment on day 1, 7 and 14 after the beginning of experiment to assess the morphologic features of the tissue fragments with destructive lesions after laser cauterization. Results. Less pronounced destructions and quicker healing were noted after the exposure to laser radiation with wavelength of 1560 nm compared to 970 nm. Statistically significant differences were revealed in general damage (U=3.5, р=0.00) and necrosis (U=0.0, р=0.00) areas depth both on day 7 and day 14 after the exposure. On day 14 no necrotic lesions were found in the second group, and general damage area was formed by granulations (U=0.00, р=0.00) compared to the first group where necrotic and inflammatory lesions persisted. Conclusion. In choosing the laser wavelength while developing rectal laser cauterization techniques for hemorrhoids, water-absorbed 1560 nm infra-red laser radiation should be preferred.
Aim. To estimate the economic efficiency of laser technology use in complex treatment of patients with benign anorectal diseases in a day ward or as an out-patients. Methods. «Mediola-Compact» semiconductor laser (manufactured by «Fotek» ldt, Belarus) was used to treat chronic hemorrhoids and chronic anal fissures. Interstitial submucosal tissue destruction device developed by authors (Republic of Belarus Patent for effective prototype №8755) was used, allowing to cause extensional destruction while inserted into the tissue. 297 surgical interventions were performed during 3 years, among them 157 patients underwent surgery while in a day ward, 140 - as an out-patients. Prevented indirect expenses like prevented admission fees, medical certificate compensations, prevented Gross Domestic Product reduction as a result of an average hospital stay reduction were assessed for economic efficiency calculation. Results. Total economic benefit of low-invasive interventions (as a reduction of expenses on admission fees and medical certificate compensations) for 3 years term in patients with anorectal diseases treated using the examined management and laser treatment methods was assessed as 140 250 US dollars. The overall economic efficiency on low-invasive laser technology is described with cost-effectiveness coefficient of 2.36, or 236%, compared to the conventional surgical treatment. Conclusion. Laser technology use in patients with benign anorectal diseases allows to significantly decrease the hospital stay using the day ward model, economic efficiency of the low-invasive laser technology as a complex treatment component in patients with chronic hemorrhoids and chronic anal fissures allows to cover the expenses for its introduction within 1 year.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.