According to WHO, the respiratory system diseases are currently inside the ten most common pathologies. The modern strategy for treating influenza and ARVI gives priority to the antiviral and immunostimulating agents, but the symptomatic drugs, which include preparations based on silver and its compounds, also play an important role. The large positive experience in using silver preparations supported by numerous clinical studies shows their high efficacy and satisfactory safety profile in the treatment of infectious and inflammatory diseases of the nose and upper respiratory tract in children and adults.
Summary. In the development of vasomotor rhinitis, many etiological and pathogenetic factors are important. This dictates the need for an integrated approach to the therapy of this widespread disease. Objective: To evaluate the effectiveness of a complex homeopathic preparation for topical application „Ointment Flemings” in the treatment of vasomotor rhinitis. Materials and methods. The study included 30 adult patients of both sexes (15 men and 15 women) aged 18 to 59 years with a diagnosis of vasomotor rhinitis. With the drug for external use, „Ointment Fleming” lubricated the mucosa of the nasal cavity or layed turuns with ointment for 3–5 minutes. 2–3 times a day. The course of treatment was 7–10 days. The effectiveness of treatment was assessed by the dynamics of clinical data and the severity of subjective symptoms of the disease. Results. Aposteriori pairwise comparisons of these ball gauges of re-evaluation of the patients' status relative to the timing of the use of the „Ointment Flemings” revealed a distinct uniform positive dynamics in the clinical picture and subjective complaints. Conclusions. Based on the studies conducted, the high profile of efficacy and safety, the complex homeopathic preparation for topical application „Ointment Flemings” is recommended for wide application in the treatment of vasomotor rhinitis.
ВВЕДЕНИЕОтогенные и риносинусогенные гнойно-воспалитель-ные внутричерепные осложнения (ВЧО) до настоящего времени являются актуальной проблемой оториноларин-гологии. По данным главных специалистов-оторинола-рингологов 34 субъектов Российской Федерации, сред-ний показатель летальности при отогенных внутричереп-ных осложнениях составил 19,7%, при риносинусогенных осложнениях -13,2%, при сочетании ото-и риносинусо-генной этиологии -34,6%. Высокий уровень летальности при данной патологии обусловлен общей тяжестью состо-яния больных при госпитализации: синдромом системно-го воспалительного ответа (ССВО), интоксикационным и очаговым поражением головного мозга [3][4]7]. Важнейшей проблемой, влияющей на результаты лече-ния больных с тяжелыми гнойно-септическими и внутри-черепными осложнениями, является сложность диагно-стики этой патологии, обусловленная полиморфизмом клинической картины заболевания [8][9][10][11].
ЦЕЛЬ ИССЛЕДОВАНИЯАнализ эффективности дифференцированного под-хода к диагностике и лечению больных с отогенными и риносинусогенными гнойно-воспалительными внутри-черепными осложнениями с использованием современ-ных критериев оценки тяжести общего состояния и стра-тификации риска. To evaluate the condition of patients and changes in course of the disease, the integral and quantifying scores to assess the severity of the systemic inflammatory response syndrome were used: SOFA, which allows to evaluate the level of organ dysfunction, the APACHE II severity of disease score and the Glasgow coma scale. The outcome is directly dependent on early comprehensive diagnosis of injury to the vital organs and systems of the body, timely initiation of specialized treatment.
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