Hypersensitivity dermatitides (HD) are commonly seen in cats, and they are usually caused by environmental, food and/or flea allergens. Affected cats normally present with one of the following clinical reaction patterns: head and neck excoriations, usually symmetrical self-induced alopecia, eosinophilic skin lesions or miliary dermatitis. Importantly, none of these clinical presentations is considered to be pathognomonic for HD skin diseases, and the diagnosis of HD is usually based on the exclusion of other pruritic diseases and on a positive response to therapy. The objectives of this study were to propose sets of criteria for the diagnosis of nonflea-induced HD (NFHD). We recruited 501 cats with pruritus and skin lesions and compared clinical parameters between cats with NFHD (encompassing those with nonflea, nonfood HD and those with food HD), flea HD and other pruritic conditions. Using simulated annealing techniques, we established two sets of proposed criteria for the following two different clinical situations: (i) the diagnosis of NFHD in a population of pruritic cats; and (ii) the diagnosis of NFHD after exclusion of cats with flea HD. These criteria sets were associated with good sensitivity and specificity and may be useful for homogeneity of enrolment in clinical trials and to evaluate the probability of diagnosis of NFHD in clinical practice. Finally, these criteria were not useful to differentiate cats with NFHD from those with food HD.

Results. In mortality from CVD structure from CVD the leading causes are ischemic heart disease (IHD) and cerebrovascular diseases (CeVD). During the period of study there was found a growth of general and primary morbidity by admittance for CVD. In the structure of general morbidity by admittance for CVD during last 10 years IHD is the leading, in the structure of general morbidity by admittance -CeVD. For the period studied, there was decrease of mortality from CVD by 22,7%, incl. 6,3% for IHD, and 1,7 times for CeVD. Conclusion. Regardless positive tendencies of last years, Chelyabinskaya region continues to be the region with high level of mortality from CVD. The revealed patterns of dynamics and structure of morbidity and mortality from CVD dictate the necessity of elaboration of the interventions for improvement of medical care for the patients with cardiovascular diseases at the level of regions.

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House dust mites seem to be uncommon in the home environment of atopic dogs in Finland despite reported frequent allergen-specific IgE antibodies.