Dagestan state medical university, Makhachkala, Russian Federation Annotation. Little is known about the mechanisms of the action of high humidity in the coastal cities on the course of coronary heart disease (CHD). Obviously, with high humidity, sweating and heat loss are difficult, and overheating increases the heart rate and exacerbates CHD. To assess the dynamics of age-related death rates from CHD, a comparative analysis of data on 11,134 deaths from CHD for 2002-2014 was conducted in the seaside town Makhachkala. The results of the study showed that mortality from CHD in Makhachkala decreased in the period 2002-2014 in men by 32.4% and in women by 40.8%, especially in young men and women aged 40-49. In the seaside town there is an increase in mortality from CHD with a low (40-50%) and high (> 70%) relative humidity, while the town Makhachkala is characterized mainly by high humidity. Thus, in the conditions of the town Makhachkala, a downward trend in the mortality rate of the population from CHD is observed, and a U-shaped relationship is observed between this index and the relative humidity of air.
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