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For the first time the current situation with tick-borne infections in recreational places of the Republic of Buryatia is evaluated. According to the data of the Center for diagnostic and prophylaxis of tick-borne infections (Irkutsk) collected in 2007 - 2014 the tick-borne encephalitis, Lyme disease, monocytic ehrlichiosis and granulocytic anaplasmosis are widely spread in most popular recreational places of south coast of the Baikal Lake and Tunka valley.

s / International Journal of Infectious Diseases 79(S1) (2019) 1-150 137 environmental and skin contaminants; however, Brevundimonas nasdae was detected in 3 out of the 6 FPLIs (50%), in addition to all of the aforementioned flora using the single assay detection protocol. Overall, the distribution of flora in ulcers of severe (n = 2) and non-severe phenotypes (n = 4) did not differ (p = 1.000).Conclusion: CL ulcers with a secondarily-infected phenotype are universally treated with broad-spectrum antibiotics, often without microbiological confirmation of presence of bacterial pathogens. Therefore, understanding the presence and complement of bacterial potential pathogens in ulcers of CL has implications for antimicrobial stewardship and evidence-based management strategies. WGS enables detection and identification of the full range of organisms present in the microbiome of the CL ulcer. Further prospective analysis, including additional WGS studies of CL ulcers, is necessary to determine the role of empiric antibiotic therapy in CL ulcers with an inflammatory phenotype.