The effect of Rh-belonging of blood in pregnants with ABO-conflict on pregnancy termination is studied. The necessity to reveal this pathology in earlier terms of pregnancy is noted. The methods of establishing the ABO-conflict during pregnancy are proposed.
Currently, with Rh isoimmunization, timely diagnosis of Rh-affiliation and the severity of fetal hemolytic disease is especially relevant to determine the time of delivery.
The possibilities of antenatal diagnosis of ABO-conflict, extremely difficult during pregnancy are studied. The proposed tactics of observation of pregnants allows to interpret properly the results of different investigation methods and to perform the appropriate treatment.
Hemolytic disease of the newborn (HDN) in Russia is diagnosed in approximately 0.6% of them [6]. There are 19 main erythrocyte group systems that combine more than 100 antigens, as well as numerous private and common erythrocyte antigens with other tissues [9]. Typically, the baby's red blood cells have some of the paternal antigens that the mother does not have. At the same time, HDN usually develops due to incompatibility between the fetus and mother for Rh or ABO antigens, rarely for other antigenic systems (due to their lower immunogenicity).
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