Responses of the neurons of the lateral and ventromedial hypothalamic regions (HL and Hvrn, respectively), as well as of the area of the dorsal hypothalamus (arid) and the projection region of the medial forelimb bundle (MFB), evoked by stimulation of the proreal cortex (field 8), cingular cortex (field 24), pyriform Iobula (periamigdalar cortex), and hippocampus (CA3) were studied in acute experiments on cats under ketamine anesthesia. Distributions of the latent periods of the responses recorded from hypothalamic neurons at stimulation of the above cortical structures were analyzed. The responses were classified into primary excitatory and primary inhibitory. Stimulation of the proreal gyrus evoked four times more excitatory responses than inhibitory responses. With stimulation of the cingular gyrus, the ratio of excitatory/inhibitory responses was 1.5:1. Stimulation of the pyriform cortex evoked activatory and inhibitory responses with a similar probability. With hippocampal stimulation, inhibitory responses appeared two times more frequently than excitatory reactions. The hypothalamus was found to be a zone of wide convergence: one-half of all responding neurons in the HL and Hvm responded to stimulations of two or more tested cortical zones. In 26~o of the cells, only excitatOry convergence was observed, while in 10~o only inhibitory convergence was found; 21 ~/~, of the cells revealed mixed convergence.
Abstract. In 2019–2020, we conducted a set of case studies devoted to the investigation and design of a methodology for GIS-based support of medical administration and planning on a city scale when accounting and controlling infectious disease. The studies were conducted for the administrative territory of St. Petersburg city (Russia), and were based upon the medical statistics data collected and accounted by St. Petersburg medical administration. The statistics included data on tuberculosis, human immunodeficiency virus and hepatitis infection. All the medical data used in the study are impersonalized. GIS-based MDMS prototype was developed upon the QGIS software.Moving forward in the previously formed study direction, now we are working on MDMS interface redesigning to facilitate its usability. Current activities are focussed on incorporation of the Web interface into previously developed MDMS prototype. The paper discusses development of the Web GIS interface prototype, and poses feature research and development aims. First feedback collected from medicals makes it possible to pose a Web-GIS-based MDMS as more flexible and easy to use, in comparison to the desktop-GIS-based.
Abstract. Medical geography and medical cartography can be denoted as classical application domains for Geographical Information Systems (GISs). GISs can be applied to retrospective analysis (e.g., human population health analysis, medical infrastructure development and availability assessment, etc.), and to operative disaster detection and management (e.g., monitoring of epidemics development and infectious diseases spread). Nevertheless, GISs still not a daily-used instrument of medical administrations, especially on the city and municipality scales. In different regions of the world situation varies, however in general case GIS-based medical data accounting and management is the object of interest for researchers and national administrations operated on global and national scales. Our study is focused onto the investigation and design of the methodology and software prototype for GIS-based support of medical administration and planning on a city scale when accounting and controlling infectious diseases. The study area is the administrative territory of the St. Petersburg (Russia). The study is based upon the medical statistics data and data collection system of the St. Petersburg city. All the medical data used in the study are impersonalized accordingly to the Russian laws.
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