There was a trend towards an increase in the percentage of patients with positive changes (a decrease in the total ADHD-DSM-IV by ≥25%) in the end of the 3rd and 4th month in the pantogam group (treatment response was 66.7 and 68.9%, respectively) compared to the placebo group (treatment response was 52.3 and 61.4%, respectively). A significant decrease in disease severity assessed by the CGI-S was noted in the pantogam group compared to the placebo group. After 4 month of treatment with pantogam, the severity of functional disturbances was reduced by 4 out of 6 WFIRS-P domains: Family, School and learning, Child's self-concept and Risky activities. Pantogam improved the measures of sustained attention (accuracy and speed) in the Toulouse-Piéron test. The drug used in mean daily dose 30 mg/kg during 4 month had a favorable safety profile which did not differ from that of placebo.
narcological department. We revealed stable patterns of combination the social demographic, clinical psychological and other factors, which are provide the opportunity to sufficient exact distinguish the individuals with substance abuse in the case of presence or absent the coexisting psychic pathology.
Objectives: The family is one of main factors, which have influence on body and mental health of the children especially in early ages. The aim of study was to explore the family status of the children with behavior disorders.
Introduction:A research of an early psychical disorder at children plays an important role in exploration of epilepsy. These children have broad spectrum of various pathological states which manifest early attacks of epilepsy (Betts T.A., 1995). The aim of current research is to learn early psychical disorders at children with epilepsy.Methods:346 children in the age of 3-18 with epilepsy and psychical, behavioral disorders were observed between attacks of epilepsy. The disorders were compared with DSM- IV.Results:In most cases (54,9%) psychical, behavioral disorders didn't have association with epilepsy and in 45,1% of cases had association with epilepsy. These disorders had four variants: the mental deficiency – 70%, the psychoorganical syndrome – 21,6%, autism spectrum disorders – 2,6% and behavioral disorders – 5,8%.190 children with psychical disorders had many injury factors in ontogenesis of brain. These factors were complicated pregnancy and childbirth, a trauma in the childbirth, negative heredity (relations these children had the mentally subnormal and addictional problems) and unfavorable environment. Children had the symptomatically, generalizationally and focally forms of the epilepsy.Conclusions:At children epilepsy may be accompanied by the mental deficiency, psychoorganical syndrome, autism spectrum disorders and behavioral disorders. These conditions have no association with debut of epilepsy but psychical disorders and epilepsy undoubtedly complicate each other making these disorders harder.
Книга содержит современные рекомендации по диагностике и лечению саркоидоза-системного заболевания, опасного своими осложнениями. Подроб но описаны закономерности формирования легочных и внелегочных проявлений саркоидоза, подходы к диагностике, оценке течения и активности, а также лечению заболевания. Издание будет интересно не только пульмонологам и фтизиатрам, но и ревматологам, нефрологам, гастроэнтерологам, гепатологам, а также врачам общей практики.
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