The deployment of the first stages of ontogenesis in all types of productive animals is determined by the change in hemostatic and rheological mechanisms. The status of these parameters strongly influences the deployment of heredity of an organism of any animal. The normal operation of the hemostasis during the neonatal strongly determines the rheological properties of blood, and therefore metabolism in the organs of young animals. Phase of neonatal calves and piglets is a serious stage of their development. Therein have the characteristic of hemostatic processes. The authors determined that during the first or second day of life in physically impaired calves and piglets develop physiologically unfavorable changes in haemostatic parameters, platelets, blood vessels and blood clotting. Emerging changes adversely affect the operation of their bodies and lead to total exclusion. The use of the drug gamavit enhances the weakened condition of newborn calves and piglets functionally acceptable reduce the activity of platelets and clotting of blood in a functionally justified the growth of the hemostatic capabilities of the vessels. It can be argued that injections of gamavit negate the existing dysfunction in hemostasis in physically weakened calves and piglets during the neonatal phase, increasing their adaptation and stimulating further growth and development of animals.
The article describes the research results on the complex enzyme and antibacterial drugs use in feed for the Hubbard cross broiler chickens. A studies review is presented, which showed that ergotropic preparations complex use when growing broiler chickens is poultry increasing the meat productivity effective method, as per basic zootechnical indicators. As a studying result an ergotropics complex combined use effectiveness in growing poultry, a significant decrease in a highly toxic elements number concentration in the broiler chickens carcasses and organs has been established, which is very important today. The preparation complex influence on the Hubbard cross broiler chickens meat chemical composition, physicochemical and tasting parameters was traced. Our research has proved the ergotropic drugs use effectiveness in broiler chickens, which is one of the increasing poultry meat productivity effective methods and the quality products necessary to provide the population needs with high nutritional and biological products values.
The normal state of hematological parameters in mammals at the beginning of ontogenesis is rightfully considered to be functionally very significant for the development of early ontogenesis in them. Hemostasis is considered to be very significant for vital functions and vulnerable blood systems. Its condition affects trophism due to the effect on the state of microcirculation, which is very important at the beginning of ontogenesis. In the neonatal phase, calves and piglets develop the formation of hemostasis and therefore, during these periods it can be easily disrupted. The appearance of hemostatic dysfunctions in the body of young animals, despite its importance, is still very poorly studied. This circumstance was the motivation for the study of the activity of the hemostatic system in calves and piglets that were born physically weakened. It was found that immediately after birth in weakened calves and piglets, there are physiologically unfavorable changes in platelet activity, vascular hemostasis and blood coagulation. This provides them with the appearance of excessive platelet activity and blood clotting with a significant weakening of vascular hemostasis. All these disorders lead to negative changes in their internal organs and create their serious dysfunctions. The development of disorders in the mechanisms of hemostasis in physically weakened calves and piglets during the neonatal phase is a serious mechanism for weakening their adaptation to the environment and slowing the growth and development of animals.
A variety of biologically active substances is used to optimize homeostasis and increase the production of pig products. Such substances include, in particular, probiotics. The fodder probiotic preparation "EM-Vita" contains microorganisms that exist in their natural habitat: lactic acid bacteria, bifidobacteria and yeast. To study the effect of different schemes of using the probiotic feed additive "EM-Vita" on the morphological composition of blood and the dynamics of live weight of pigs, taking into account the breed, age and live weight, the paired analogues method was used to form 3 groups of 10 heads of weaned piglets 46-53 days old, live weight of 11.18 ± 0.01 kg. Animals of group 1 were control, pigs of group 2 received once a day, 4 ml of feed supplement "EM-Vita" for 2 months according to the scheme:-7 days-feeding, 7 days-a break; pigs of the 3rd group-also received once a day 4 ml of feed additive "EM-Vita" for 2 months: according to the scheme:-7 days-feeding, but a break-14 days. Blood for the study was taken from 5 animals from each group from the jugular vein in the morning before feeding before the start of the experiment, after 1 and 2 months of drinking the drug, and one month after the end of drinking it. 6 days before the third blood sampling, all pigs were vaccinated against Auesca's disease and swine erysipelas (Vetbiochem LLC). It was established that the use of probiotic drug "EM-Vita" when growing pigs for 2 months according to both schemes caused an increase in the body's reactivity, which is indicated by an increase in the blood level of neutrophils, monocytes and a decrease in the level of lymphocytes 6 days after vaccination of animals. At the same time, a more rapid restoration of optimal homeostasis one month after the end of feeding the drug, as evidenced by a decrease in the number of neutrophils and monocytes in the blood with an increase in the number of lymphocytes, and a higher live weight was observed in pigs who were fed with EM-Vita for 2 months, According to the scheme:-7 days watering, 14 days-a break.
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