The analysis of course of pneumonia in 33 children with various forms of infantile cerebral palsy (ICP) had been conducted. It is determined that more severe course of pneumonia with distinct, long‐lasting symptoms of respiratory failure and fever was observed in double hemiplegia with spastic tetraplegia and distinct muscle hypertension; atonic‐astatic with low muscle tone and impairment of cortical‐subcortical connections; hyperkinetic with hyperkinesia. These patients had stayed long in the intensive care department (an average of 29 ± 3,2) with artificial lung ventilation. Persistence and distinction of respiratory symptoms were supported by the presence of GORD, microaspiration, vomiting, impaired swallowing reflex (85.7%). This entails that all patients with ICP should regularly examine lung function, even in the absence of respiratory symptoms, examine for finding the presence of pathology of aspiration, select special breathing techniques in ineffective cough reflex.
Bronchial asthma is a common multifactorial disease in children requiring long‐term therapy to achieve control, focuses on the need for anti‐inflammatory therapy, regardless of the severity of clinical manifestations.Material47 children have been examined with diagnosis – bronchial asthma during exacerbations (4), the rest ‐ in the period of clinical well‐being. 26 children expressed medium‐heavy course (55.3%), severe ‐ in 21 children (44.7%). The average age of the patients was 5,0±2,4 (30 boys and 17 girls aged from 2 to 14 years), duration of the disease 4,05±3.1. All children had symptoms of the disease all year ‐ round, remission lasted no more than 4‐5 months per year.Changes of bronchial mucosa have been revealed during the fibrobronchoscopy of children with asthma in all cases. Frequency of atrophic/subatrophic symptoms has been increased and hyperplasia/hypertrophy is decreased with increasing duration of the disease. Symptoms atrophy subatrophy mucous found in 55.3% of cases. Signs of atrophy often determined on the right, sometimes on both sides or on the left. Pathological secretion in the bronchi found in 40 patients (85.1%), and in attack period in all cases and in remission ‐ in 80.8%. A microscopic and microbiological examination of broncho‐alveolar fluid has been conducted. Elevated levels of neutrophils to 12,6±0,07% to 17,5±2,2% and reduced ‐ macrophages with 24,8±1,6% to 20.7±0,8% (p<0.05) have been found with increasing severity of asthma. Morphological analysis of bronchobiopsy in patients with asthma found that the heavy course is characterized with more intense sloughing of the mucosa and thickening of the basement membrane ‐ as a biological marker of disease severity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.