Purpose: to develop an effective and affordable method for a practical doctor to predict the development of bacterial pneumonia in patients with influenza and other acute respiratory viral infections. Materials and methods: to develop a method for predicting bacterial pneumonia in patients with influenza and other acute respiratory viral infections, a continuous group of 247 patients was formed: 63 of them were diagnosed with bacterial pneumonia for 5-7 days of illness, and the remaining 184 had verified infectious diseases in uncomplicated form. Evaluation of the effectiveness of the proposed forecast method was performed on 150 patients with influenza and other acute respiratory viral infections. The technical basis of this study was the Extech 110 pH meter, with which the observed acidity of the skin of the lower third of the palmar surface of the forearm was studied on the 1-2, 3-4, 7-10 days of the disease. Results: the developed method for predicting bacterial pneumonia in patients with influenza and other acute respiratory viral infections is characterized by prostate use, as well as high rates of sensitivity, specificity and accuracy.Conclusions: the pH level of the skin of the palmar surface of the lower third of the forearm in patients with influenza and other acute respiratory viral infections of less than 4.80 is a statistically significant prognostic criterion for the development of this category of patients in the next 2-3 days of bacterial pneumonia.
Background: many researchers report numerous predictors of severe COVID-19 and poor prognosis. However, to make a quick decision, the doctor needs to have a certain set of data that he can use in routine practice to predict the outcome in patients with this disease. Aims: develop and describe a predictive model for determining an unfavorable outcome in COVID-19 patients based on age, objective, laboratory and instrumental data and comorbid pathology. Materials and methods: the study included 447 patients with a laboratory-confirmed diagnosis of COVID-19 who underwent inpatient treatment in the period from March to August 2021. Discriminant analysis was used with cross-validation to build a predictive model. Results: Based on discriminant analysis, a predictive model was developed to predict outcome in patients with COVID-19. Evaluation of clinical findings such as respiratory rate, heart rate, SpO2, laboratory data and computed tomography results on admission to the hospital showed their significance as predictors of poor outcome. The discrimination constant was 0.4435. The sensitivity of the model is 96.4%, the specificity is 90.4%. Conclusion: the developed model will help medical institutions predict the outcome of the disease when a patient is admitted to the hospital and, on this basis, optimize and prioritize the provision of necessary medical care.
Tis review describes different virus taxa that are more prevalent in some variants of urological pathology. Te search of articles was conducted in the information portals of Te Cochrane Database, MEDLINE / PubMed Database, eLIBRARY, ClinicalKey for the period 2008-2018. As a result, the most current and representative studies, containing an interpretation of the dynamics of opinions indicating the involvement of viruses in various urological diseases were selected. Te bacterial component is the most studied in the etiology and pathogenesis of inflammatory diseases, but the viral component, as a rule, remains outside the scope of routine examination of patients, which stagnates conducting of adequate therapy and prevention of infectious and inflammatory diseases in urology.
Purpose: to develop an effective and safe method for the etiopathogenetic treatment of influenza patients, aimed at increasing the effectiveness of the existing standard treatment using the antiviral drug oseltamivir.Materials and methods: 150 patients with a verified diagnosis of influenza were taken under observation. All of the participants were divided by randomization into two groups (n1 = 77, n2 = 73) which had the same initial clinical and laboratory characteristics. I group’s patients received standard antiviral therapy using oseltamivir. Patients of the II group at the same time as oseltamivir additionally received an aqueous solution of rehydron for 5 days. All patients underwent determination of the acidity of the mucous membrane of the oropharynx immediately before the start of antiviral therapy and immediately after its completion.Results: patients additionally receiving rehydron had a more rapid leveling of the main symptoms of influenza and a decrease in the frequency of its complications compared with people who received only standard treatment.Conclusions: the developed method of etiopathogenetic treatment of patients with influenza is characterized by a proven level of effectiveness, which is associated with the corrective effect of rehydron on the acid-base balance of the mucous membranes of the respiratory tract. The data obtained in the course of the study indicate not only the absolute scientific novelty of the developed method, but also its applied significance for practical public health.
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