Background. Psoriasis is a systemic disease with the presence of comorbid pathology, which is the cause of serious psychological problems. The aim of the study was to assess the quality of life and psychoemotional status of patients with psoriasis against the background of standard drug therapy with the inclusion of photochromotherapy (PCT). Methods. The randomized controlled study included 144 patients (mean age 48.34 13.51 years) with psoriasis in the advanced stage. Patients, depending on the method of treatment, were divided into 4 groups, comparable by clinical and functional characteristics. For all groups, standard drug treatment was prescribed, including antiinflammatory, hyposensitizing, detoxification and external therapy, while additionally for 10 days, patients of the 2nd group (n = 47) received PCT with narrow-band optical radiation (NOR) 540 nm, patients of the 3rd group (n = 48) PCT with NOR 650 nm, patients of the 4th group (n = 21) imitation of PCT (placebo). Patients of the 1st group (n = 28) received only standard treatment. Results. The positive effect of NOR 540 nm on the psychoemotional state and NOR 650 nm on the quality of life of patients with psoriasis has been demonstrated. Conclusion. Thus, taking into account the significant positive effect of green radiation (NOR 540 nm) on the indicators of the psychoemotional state of patients with psoriasis in the advanced stage and the positive effect of red radiation (NOR 650 nm) on the indices of integral dermatological index of quality of life (improving the quality of life), NOR with these wavelengths can be recommended in the complex therapy of patients with exacerbation of psoriasis to increase the overall effectiveness of treatment.
Introduction: Functional recovery of voice function in patients with laryngeal dysfunction is a slow and lengthy process that is associated with changes in social and economic living conditions. The serious functional damage can also lead to disorders in swallowing and respiratory function. It is believed that paresis passes into definitive if continues for more than 10-12 months due to irreversible changes in the tissues. According to literature data, spontaneous recovery in unilateral vocal cord paralysis is observed in 40% of cases. Low frequency currents with adjustable parameters are frequently used in the practice of electro diagnostics and electrical stimulation in damage of the neuromuscular system and in particular in laryngeal paresis and paralysis. In recent decades, an increase in the number of patients suffering from diseases associated with laryngeal dysfunction was noted by many authors. Interruption of nervous pulsation to laryngeal structures leads to sensory and motor disorders and development of subsequent paralysis of the muscles. Treatment depends on the cause, the severity of the symptoms and time of onset of the disease. It includes non-operative and operative treatment. Non-operative treatment is with good results and should precede surgery. Purpose: The purpose of this study is to objectify the therapeutic options of neuromuscular elektro-phonatory stimulation /NMEPS/ in patients with laryngeal dysfunction. Materials and methods: The study included 21 patients with unilateral dysfunction of n. laryngeus recurens after surgery of the thyroid gland. Patients with complete denervation were excluded from the study. Procedures are preceded by electro-diagnostic in direct laryngoscopy to establish the extent of damage of the nerve and to determin the coefficient of accommodation (ACC) and variable parameters for stimulus currents. Therapeutic session is implemented in two stages: (1) 'heating' with galvanic current, and (2) real NMEPS selective stimulation of the damaged muscle, leaving untreated antagonists or neighboring healthy muscles, accompanied by active and targeted implementation of Förster phonatoric exercises, coughing and breathing. Treatment is organized in courses for 10 days, 20 procedures per course. Results: The results before and after completion of therapeutic course by assessing changes in the coefficient of accommodation(ACC), voice quality, degree of hoarseness, coughing efficiency, presence of dysphagia are reported. After statistical processing of the obtained results a statistical dependence in relation to dysphonia before and after NMEPS therapy was established (p=0.0001), which is expressed in improvement of medium to mild dysphonia. In relation to dysphagia we found improvement from average-heavy to light form of dysphagia and absence of any symptoms of it after treatment, but there are patients with no change observed (44.4%) and statistical dependence (p=0.005) Patients with dysfunction regarding the effectiveness when coughing, before treatment they were: 16.7%, with severe dysfunction, 50.0% with moderate to severe and 33.3% with light. After NMEPS therapy improvement in the condition of patients with moderate-heavy to light form was observed. The non-parametric analysis proved statistical dependence (Z=3.58 ;p=0.0001). All patients were asked to assess the quality of their voice according to the Linkert five-point rating scale. In the beginning of the therapy 44.4% of the patients ranked their voice quality as poor, 50.0% as moderate and 5.6% as good. After treatment improvement in self-assessment of voice quality from moderate to very good and statistical dependence (p=0.0001) was observed. Conclusion: The results of the observational study prove that NMEPS therapy is effective for functional recovery in complex treatment of laryngeal dysfunction. Because of the small number of patients included in the study for better objectifying of the effects of the neuro muscular elektro-phonatory stimulation, the studies should continue.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.