Assessment of quality of life and psychoemotional state of patients with psoriasis against the background of standard medicamentous therapy and the differentiated photochromotherapy use

Abstract

Background. Psoriasis is a systemic disease with the presence of comorbid pathology, which is the cause of serious psychological problems.
 The aim of the study was to assess the quality of life and psychoemotional status of patients with psoriasis against the background of standard drug therapy with the inclusion of photochromotherapy (PCT).
 Methods. The randomized controlled study included 144 patients (mean age 48.34 13.51 years) with psoriasis in the advanced stage. Patients, depending on the method of treatment, were divided into 4 groups, comparable by clinical and functional characteristics. For all groups, standard drug treatment was prescribed, including antiinflammatory, hyposensitizing, detoxification and external therapy, while additionally for 10 days, patients of the 2nd group (n = 47) received PCT with narrow-band optical radiation (NOR) 540 nm, patients of the 3rd group (n = 48) PCT with NOR 650 nm, patients of the 4th group (n = 21) imitation of PCT (placebo). Patients of the 1st group (n = 28) received only standard treatment.
 Results. The positive effect of NOR 540 nm on the psychoemotional state and NOR 650 nm on the quality of life of patients with psoriasis has been demonstrated.
 Conclusion. Thus, taking into account the significant positive effect of green radiation (NOR 540 nm) on the indicators of the psychoemotional state of patients with psoriasis in the advanced stage and the positive effect of red radiation (NOR 650 nm) on the indices of integral dermatological index of quality of life (improving the quality of life), NOR with these wavelengths can be recommended in the complex therapy of patients with exacerbation of psoriasis to increase the overall effectiveness of treatment.