A brief review of the literature devoted to the rare eosin-filed granulomatous necrotizing vasculitis ChurgStrauss syndrome is given. Two clinical cases of this disease are presented from the personal practice of the authors. The complexity of diagnostics was emphasized; it contributed to the fact that the disease lasted for a long time under the guise of other nosologies which later turned out to be syndromes of vasculitis ChurgStrauss. When pulmonary infiltrates occur in patients with asthma with allergic rhinitis or rhinosinusopathy in combination with high eosinophilia of peripheral blood and neurologic symptoms, it is necessary to suspect the Churg-Strauss syndrome and conduct appropriate diagnostic measures.
Chronobiological aspects of blood gas composition in 24 patients with COPD were studied. To achieve this goal, the gas composition of the arterialized capillary blood simultaneously with the investigation of respiratory function was studied with an interval of 6 hours over 2 days. In healthy individuals and patients with mild COPD two types of gas composition of blood biorhythm – daytime and nighttime – were found. In patients with moderate, severe and very severe disease 3 types of biorhythm of partial oxygen and carbon dioxide tension – morning time, noontime and evening time were registered. In healthy individuals and patients with mild COPD gas composition of blood was characterized by significant degrees of freedom in relation to functioning of the respiratory system, which indicated the stored processes of adaptation to changing conditions of the external and internal environment. In patients with moderate, severe and very severe COPD at the moment of acrophase of circadian rhythm of lung function maximum partial oxygen pressure in the arterialized capillary blood was observed. During the batiphaze of circadian rhythm of the respiratory system the highest values of the partial carbon dioxide tension were revealed. Thus, it was found out that with the growth of the severity of the disease in patients with COPD abnormal rhythms of blood gas composition are registered; the dependence of circadian rhythm of blood gas composition on the functioning of the respiratory apparatus increases.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.