In the article the questions of diagnostics and treatment of patients with recurrent papillomatosis of larynx, singular papillomas and various forms of chronic hyperplastic laryngitis from the present-day view-points have been presented. The most optimal schemes of treatment for recurrent papillomatosis of larynx were suggested.
This review paper presents the results of the recent studies designed to elucidate the etiopathogenetic role ofhuman papilloma virus infection in the development of respiratory papillomatosis in the children. Special attention is given to the possible pathways and mechanisms of the mother-to-child transmission of papilloma virus, its frequency and risk factors during pregnancy and in the postnatal period. The results of investigations into the frequency of papilloma virus infection in the children are presented along withrisk factors contributing to its persistence and the development ofjuvenile respiratory papillomatosis. The possible approaches to the management of this condition are proposed.
Ninety-two families with spinal muscular atrophy (SMA) applied for genetic counselling and further prenatal diagnosis. To minimize expenses, only one tightly linked informative marker was determined in the course of preliminary examination, and non-radioactive allele detection was preferably used. Four prenatal diagnoses of SMA type I, four of SMA type II, and one of SMA type III were made. This trial programme shows the considerable requirements, importance, and potential effectiveness of prenatal prediction of SMA in Russia.
In the article the possible ways of HPV prevalence in children in the family circle have been examined, as well as the probability of each of the possible transmission ways has been assessed for the infection manifestation in different age groups. The possibilities of preventive measures against infection of children in the present-day conditions were considered.
Efficacy of adenotomy in two groups of patients (with hypertrophy of pharyngeal tonsil and chronic adenoiditis) was investigated. The investigation revealed that children with adenoiditis have shown better nasal breathing in distant period than children with adenoid hypertrophy without accompanying adenoiditis. We propose to consider chronic inflammation of pharyngeal tonsil as positive predictor for quality of nasal breathing after surgery. In children with pharyngeal hypertrophy without chronic adenoiditis partial adenotomy under endoscopic visual control is more preferable to preserve its immunological function.
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