The objective. To assess and compare the multi-modal evoked potentials (EP) (flash visual [fVEP], brainstem acoustic [BAEP] and cognitive evoked responses [CER]) parameters in children with cerebral palsy (CP) and healthy ones.Materials and methods. There are 100 children aged 3–17 years were examined. Experimental group included 55 children with CP, diagnosed according to International cerebral palsy criteria (P. Rosenbaum et al., 2006), and mild motor deficit (levels I–II of Gross Motor Function Classification Scale), undergoing rehabilitation course. Control group was presented by 45 healthy children aged 3–17 years with no neurological signs. Registration of the fVEP, BAEP and CER and their comparative analysis with non-parametric tests was performed. Neurophysiological recording performed on EMG-VP4 system (MBN Scientific Company, Moscow, Russia).Results. Slowing of maturation and significant delaying of main EP components were observed in experimental group.Conclusion. Findings in this investigation indicate the retardation of cortical sensory processing in children with CP. Analyzing multi-modal EP may be helpful in early detecting sensory abnormalities as complications of CP.
Background. In children with cerebral palsy, high risk of cognitive impairments connected with sensory disintegration – delayed visual and auditory perception.The objective – assessment of temporary and amplitude characteristics brainstem auditory evoked potentials of children with cerebral palsy.Materials and methods. Neurological examination, retrospective analysis of magnetic resonance imaging data of brain and 2-channel brainstem auditory evoked potentials registration with left- and right-ear stimulation and analysis was performed for 60 children aged 4–17 years, with mean age 11.80 ± 0.56 years.Results. There are no significant difference in brainstem auditory evoked potentials latencies of children’s with cerebral palsy age subgroups. A significantly increasing of III–V peak latencies of brainstem auditory evoked potentials and also I–III and I–V interpeak latencies was observed in children with cerebral palsy in comparison of control group. Latencies of different brainstem auditory evoked potentials peaks were significantly higher in children with uni- and bilateral form of cerebral palsy and speech impairment. Group with periventricular leucomalation (on magnetic resonance imaging) is characterized by significantly increased brainstem auditory evoked potentials latencies and normal interpeak intervals. These abnormalities may be linked to non-progressive impairment of brainstem acoustic afferentation.Conclusion. Impairment of brainstem auditory evoked potentials maturation and it’s difference in various cerebral palsy forms may be potentially clinical applicable for assessment of the children and early detection of sensory impairment.
Introducion. Children with cerebral palsy demonstrate high prevalence of the cognitive impairment (CI). One of the key components of CI pathogenesis is sensory disafferentation. Aim. The goal of this investigation is to perform comparative analysis of event-related potentials (ERP) in children with CP and in healthy children. Materials and methods. A total of 30 children with CP (mean age 8.9 ± 0.84 year) and 44 healthy subjects (mean age 9.5 ± 0.60 years) were observed. Registration and comparative analysis of the acoustic ERP were performed with the use of non-parametric tests. Results. The decrease in age-related ERP latencies was slower in the main group. Significant elongation of ERP latencies was also observed in the main group, despite the clinical absence of cognitive decline. Conclusions. Our findings confirm the theory of sensory information cortical processing delay in children with CP. More investigations should be performed for the assessment of reliability of the ERP in the objective evaluation of CI level.
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