Aim -Investigation of features of interaction between the loops of autonomic control of heart rate and vascular tone under the ataractanalgesia and spinal block. Material and Methods -The contemporary nonlinear methods developed for the analysis of complex non-periodic signals were applied to the study of electrocardiogram (ECG) and photoplethysmogram (PPG) signals from women during minor gynecological operations. The registered signals were the single-channel ECG at the II standard lead and three channels of PPG (from earlobe, right ring finger, and right second toe). These signals were recorded under resting conditions at 60 minutes before the surgery and during the main stage of operation under the spinal anesthesia and ataractanalgesia. The signals were sampled at a frequency of 250 Hz and filtered in the 0.05-0.15 Hz band, which includes the rhythms of autonomic control of heart rate and vascular tone.Results -The analysis of phase dynamics of the studied oscillatory systems revealed that the spinal anesthesia suppresses the coupling between the rhythms of autonomic control of heart rate (extracted from ECG) and vascular tone (extracted from PPG) but in a less degree than general anesthesia induced by ataractanalgesia. The strength of the detected coupling between the heart rate variability and PPG depends on the distance between the body parts from which the ECG and PPG signals were recorded. The coupling was found out to be stronger for smaller distances. Conclusion -The obtained results may have not only diagnostic, but also prognostic importance for the estimation of circulatory failure during operations under surgical anesthesia.
ФГБОУ ВО «Саратовский государственный медицинский университет им. В.И. Разумовского» Минздрава России, Саратов, Россия РЕЗЮМЕ Хирургическая анатомия и оперативная хирургия грыж, разработанная выдающимся ученым анатомом и хирургом С.И. Спасокукоцким, является «золотым фондом» отечественной хирургии. Научные и практические достижения хирургической школы С.И. Спасокукоцкого характеризуются глубоким и тщательным анализом клинических наблюдений, построенным на основе богатого и весьма разнообразного материала исследований, стройной системой хирургического лечения грыж, соответствующей современному уровню медицинской науки.
Objectives to prove the effectiveness of the new developed method of treatment of patients with localized superficial and partial thickness burns (gel and silver coating plus ultraviolet radiation of the wound and magnetic therapy). Material and methods.The treatment of local burn wound infection was analyzed in 29 patients with I-II degree localized burns during the all phases of the wound healing process. The wound material was obtained in accordance with the requirements of the Guidelines МУ 4.2.2039-05 "The technique of collection and transportation of biomaterials in microbiological laboratories". The material was delivered to the laboratory in test tubes with a transport medium under isothermal conditions at a temperature of 2022C within a day after collection. Results.The tests revealed no significant differences in the studied characteristics between the compared groups (р0.05, р=0.55,2=3.841). Conclusion.We consider the developed method of local treatment of superficial and partial thickness localized burns as a rather promising, feasible method having its own significance and intended for the prevention and treatment of local wound infection in all phases of the wound healing process.
Aim. Search for a more advanced technique for installing a mesh implant during ventroplasty of the anterior abdominal wall.Materials and methods. Modeling of prosthetic venteroplasty was carried out using laboratory animals - rabbits weighing 2000±50 g and rats weighing 400±50 g. As part of the experiment, implantation mesh material was used: "Prolene" and "REPEREN". Ventroplasty was performed using the following techniques: onlay, inlay and sublay. The implant was fixed with a continuous suture. On the 21st day of the experiment, the material was collected to study its biomechanical and morphological properties.Assessment of the morphological properties of preparations stained with hematoxylin-eosin and picrofuchsin according to Van Gieson was performed by histological methods. Biomechanical properties were evaluated using an INSTRON-5944 bursting machine.Results. In the course of comparing the biomechanical properties of the abdominal wall with the maximum value of load (H), stress (Mpa), and Young's modulus, the following results were obtained, a significantly significant dependence of the biomechanical and morphological properties of prosthetic ventroplasty on the mesh implant suturing technique was confirmed, and the advantages of sublay separation ventroplasty technology were scientifically substantiated.Conclusion. The experiment made it possible to confirm the dependence of biomechanical and morphological properties of prosthetic ventroplasty on the technique of mesh implant stitching used, to substantiate the advantages of separation ventroplasty using sublay technology.
Динамика объема полости абсцесса мягких тканей при его комбинированном лечении в эксперименте В.В. АЛИПОВ, А.И. УРУСОВА, М.С. ЛЕБЕДЕВ, Д.А. АНДРЕЕВ, М.В. ЖЕЛАЕВ ФГБОУ ВО «Саратовский ГМУ им. В.И. Разумовского» Минздрава России, Саратов, Россия Цель исследования. Оценить динамику объема гнойного абсцесса мягких тканей (ГАМТ) при его комбинированном хирургическом лечении с использованием наночастиц оксида цинка (НОЦ) на основе препарата эплан. Материалы и методы. В 80 экспериментах четырем группам лабораторных животных (крысы-самцы массой 250±50 г) моделировали ГАМТ стафилококковой этиологии, животным 4-й группы проводили комбинированное хирургическое лечение с применением НОЦ на основе препарата эплан. Результаты. Комбинированное применение эплана и НОЦ способствует ускоренному процессу регенерации и сокращению размеров полости абсцесса, а также практически полной облитерации полости уже к 10-му послеоперационному дню. Заключение. Применение комбинированного хирургического лечения за счет усиления процессов коллагеноза и эпителизации тканей создает оптимальные условия для облитерации полости и в 2 раза сокращает сроки лечения абсцесса. Ключевые слова: гнойный абсцесс мягких тканей, объем полости абсцесса, эксперимент, моделирование.Objective. To estimate the time course of changes in the volume of soft tissue abscess (STA) during its combined surgical treatment using eplan-based zinc oxide nanoparticles (ZONs). Material and methods. In 80 experiments, Staphylococcus-induced STA was simulated in four groups of laboratory animals (male rats weighing 250±50 g); Group 4 animals received combined surgical treatment using eplan-based ZONs. Results. The combined use of Eplan and ZONs contributes to the accelerated regeneration process, reduced abscess cavity, and almost complete cavity obliteration just at 10 postoperative days. Conclusion. Combined surgical treatment, by strengthening the processes of collagenosis and tissue epithelialization, creates optimal conditions for cavity obliteration and results in a twofold reduction in the time of abscess treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.