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Paroxysms with accompanying nausea were found in 90% patients. Acute nausea was associated with older age, earlier onset and longer experience of migraine. In a group of patients with acute nausea, the frequency and intensity of migraine paroxysms, probability of reoccuring pain in the first day and the severity of social disability were higher. Development of nausea in between the paroxysms and its intensity was significantly higher in patients with high intensity of nausea in migraine paroxysms. Nausea in the prodrome was significantly associated with migraine without aura and chronicity of the disorder. Patients with nausea in the prodrome also had a longer painful phase and more severe social disability. No relationship between organic diseases of the digestive tract and nausea was found. Nausea can have its own pathological mechanisms not related to concomitant diseases of the digestive tract that should be taken into account in therapeutic interventions aimed at improving quality of life of the patients.

ТОМ 7 VOL. 7Нервно-мышечные Б О Л Е З Н И Neuromuscular DISEASES

107 patients with discirculatory encephalopathy were examined. The main syndromes of the disease were a mild cognitive impairment, vascular parkinsonism, pseudobulbar, ataxia. Сorrelations between level cholesterol, lipoproteids low density in the blood with extent of atherosclerosis in the carotid artery and cognitive functions were analysed. The presence of atherosclerotic plaques, not thicking of intima-media complex, correlates with changes of memory and attention.