Abstract. This article is devoted to the role of cytological and virological screening in the secondary prevention of cervical cancer. Five hundred and fifty two cases of carcinoma in situ (of cervical cancer) and 1248 cases of invasive cervical cancer over a period of 15 years were analyzed. This period has separated into three stages: I — 1998–2002, II — 2003–2007, III — 2008–2012 years. Cervical cancer morbidity in Karelia is reported to increase tripled from 10.5 to 30.5 causes per 100 thousand women population. The excess incidence has identified among young women in reproductive age including an age group 30 year. It has been noticed that the detection rate of carcinoma in situ was statistically significant increased from 24.34±9.2% in 1998–2002 to 62.8±20.9% in 2008–2012 years. There are three different level regional groups of early cervical cancer detection (0–I–II stage) in the Republic of Karelia. Despite of the fact, that the cervical cancer is increas-ing significantly, there are a good results of its early diagnostics, thanking to the cytological and virological screening in Karelia.
2014, Т. 4, № 2 Иммунитет и рак шейки матки group) in comparison with a surgical treatment only (the control group) have been conducted. The true numerical normalization of subpopulation composition of peripheral blood lymphocyte has been determined including the expression level of suppressor lymphocytes molecular markers (FOXP3 и TGF-β1) and the expression level of CD95-marker in a study group in comparison with a control group. Moreover, true decrease of HPV (human papillomavirus)-positive patients (1.7%) and the absence of E7 oncoprotein in the study group have been discovered.
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