We developed a translation model of alcoholic cardiomyopathy in rats. By the end of forced alcoholization (the rats received 10% ethanol solution as the only source of fluid for 24 weeks; mean daily ethanol consumption was 5.0-6.5 g/kg), the rats developed dilated heart failure. Echocardiography and morphometric study of the myocardium revealed a decrease in inotropic function of the heart and dilatation of the right and left ventricles. Fatty degeneration of the myocardium (pathognomonic sign of alcoholic cardiomyopathy) and decrease in electrical stability of cardiomyocytes reliably reproduce the clinical pattern of alcoholic cardiomyopathy.
Introduction: Nowadays, studying the features of influence of mobile devices on stereotypes of children’s
behavior and communication between children and adults acquires special significance. In modern conditions, a child
loses the need for verbal communication and physical activity devoting almost all leisure time to virtual space. As
a result, along with the development of specific features of cognitive functions in children their physical activity reduces
significantly posing health risks and contributing to excess body weight, obesity, diseases of cardiovascular
and nervous systems. Our objective was to evaluate the effectiveness of restrictions imposed on the use of cellphones
at schools. Materials and methods: The study was conducted in Novosibirsk in January – March 2020. It involved 454
school children including 228 children who did not use cellphones during school breaks (observation group) and 226
children who actively used cellphones during breaks and lessons (control group). Results: The observation group was
characterized by significantly higher energy expenditures related to physical activities with a dynamic component
during breaks (p≤0.05) as confirmed by objective data collected by a Polar V800 pulsometer with Polar H10 heart rate
sensors, a higher percentage of verbal communications (81.2% against 21.2%), a lower prevalence of posture disorders
as detected by computer topography (32.8% against 65.8%) and signs of overexertion of the visual apparatus during
the school day among the children having functional visual loss (34.6% against 69.2%). Conclusions: The results prove
the effectiveness of restrictions imposed on the children’s use of cellphones at school.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.