This large population-based study suggests that use of risperidone and olanzapine increases risk of pneumonia compared with use of quetiapine in elderly patients. This study provides new information on the comparative risk of pneumonia associated with different atypical antipsychotics in the elderly to support optimal treatment decisions.
The study explored University students' utilization, attitude, and behavior towards mHealth apps and investigated subgroup variations in mHealth app use. Methods: The survey was administered to the students of St. John's University, Jamaica, New York. A non-experimental cross-sectional survey was employed. An in-person, paper and pencil-based survey method were used to collect data. Data was analyzed on SPSS 24. Results: The survey of 251/260 students were included with a response rate of 96.54%. Amongst 54.98% were users and 45.02% were non-users of mHealth apps. The use of mHealth apps found high in females 59% than males 44.5%. A majority 78.5% of participants reported themselves as IOS users and 20.7% as Android users. Nearly 38% of respondents use their mHealth apps a few times a week followed by a few times a day 15.9% and once a day 15.2%. Among users, 94.9% reported the use of mHealth apps for wellness management and 26.8% reported the use of mHealth apps for disease and treatment. Approximately 82% of users selected mHealth apps for physical activity/fitness purposes, 42.8% as a food-calorie counter and 42% for dieting/ weight loss. About 70% of the participants mentioned ease of use of the app as an important factor for choosing a particular mHealth app, followed by 60% who mentioned usefulness. Other considerations found were reviews/ratings 48.6%, and price 42%. With nonusers, almost half 49.6% of the respondents marked lack of usefulness/don't find useful as the most important factor for not using mHealth apps followed by lack of knowledge/ availability 38.1%. The mean and standard deviations were 7.92 (1.50) and 7.11 (1.71) for attitude-behavior respectively out of a possible score range of 2 to 10. Conclusions: The results revealed the user students of mHealth apps outnumbered non-users and possess a positive attitude and behavior towards mHealth apps.
2021): Risk and cost of infection-related hospitalizations in medicare beneficiaries with comorbid rheumatoid arthritis treated with abatacept versus other targeted disease-modifying anti-rheumatic drugs, Journal of Medical Economics,
Fluoride is a chemical compound known to bring about fluorosis. It is thought to disrupt the central nervous system because of its ability to induce excitotoxicity and oxidative stress. Any damage of pyramidal cells in the prefrontal cortex would result in cognitive function and working memory regulation disorders. The present study aimed at investigating the effects of sodium fluoride (NaF) on the working memory and estimated total number of medial prefrontal cortex pyramidal cells of adult male rats. Thirty-two male Wistar rats were assigned into four groups, namely control and three treated groups receiving 5, 10 and 20 mg/kg BW, respectively, of oral NaF solution for 30 days. The working memory test was carried out using a Y-maze. The number of pyramidal cells in the medial prefrontal cortex was estimated using an unbiased stereological method. There was no significant difference among groups in the working memory and number of pyramidal neurons in the medial prefrontal cortex cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.