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Firstly, the historical background is presented for the determination of ultimate bearing capacity of shallow foundations. The principles of plastic equilibrium used in the classical formulation of the ultimate bearing capacity are reviewed, followed by a discussion about the sources of approximations inherent in the classical theory. Secondly, based on a variety of case histories of site investigations, including extensive bore hole data, laboratory testing and geophysical prospecting, an empirical formulation is proposed for the determination of allowable bearing capacity of shallow foundations. The proposed expression corroborates consistently with the results of the classical theory and is proven to be reliable and safe, also from the view point of maximum allowable settlements. It consists of only two soil parameters, namely, the in-situ measured shear wave velocity, and the unit weight. The unit weight may be also determined with sufficient accuracy, by means of another empirical expression, using the P-wave velocity. It is indicated that once the shear and P-wave velocities are measured in-situ by an appropriate geophysical survey, the allowable bearing capacity is determined reliably through a single step operation. Such an approach, is considerably cost and time-saving, in practice.

This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Highlights • A numerical analysis framework has been developed that captures the experimentally observed dynamic response of micro-lattices • The framework has been demonstrated to be accurate and robust across two lattice geometries and two loading rates, with responses monitored at both the impact face and the distal face of the sample • The results suggest that simple MDoF models can be developed to capture the response of such geometries under fast loading regimes 1

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Summary Eighteen 1-phenyl-, 1-thiocarbamoyl-and 1-N-substitutedthiocarbamoyl-3-phenyl-5-heteroaryl-2-pyrazoline derivatives were synthesized and tested for their antidepressant and anticonvulsant activities. Their chemical structures were proved by spectral and microanalysis. The antidepressant activities of the compounds were investigated by the ?forced swimming test?. Results showed that compounds II-a,b,c, III-1b,1c,4a showed activities equivalent to or higher than pargyline hydrochloride (CAS 306-07-0) and tranylcypromine sulfate (CAS 13492-01-8) that were used as reference antidepressant drugs. Anticonvulsant activities of the compounds were determined by maximal electroshock seizure (MES), subcutaneous metrazol (ScMet.) and rotarod toxicity tests in mice according to the phase I tests of the Antiepileptic Drug Development programme. Compounds I-a, II-a,b,c, III-1b,2a,2c were found protective against MES and III-1b,1c,2a,2c were found protective against ScMet.

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Elastic theory shows that wide spectrum signals in the Hopkinson pressure bar suffer two forms of distortion as they propagate from the loaded bar face. These must be accounted for if accurate determination of the impact load is to be possible. The first form of distortion is the well-known phase velocity dispersion effect. The second form, which can be equally deleterious, is the prediction that at high frequencies, the stress and strain generated in the bar varies with radial position on the cross section, even for a uniformly applied loading. We consider the consequences of these effects on our ability to conduct accurate backward dispersion correction of bar signals, that is, to derive the impact face load from the dispersed signal recorded at some other point on the bar. We conclude that there is an upper limit on the frequency for which the distortion effects can be accurately compensated, and that this can significantly affect the accuracy of experimental results. We propose a combination of experimental studies and detailed numerical modelling of the impact event and wave propagation along the bar to gain better understanding of the frequency content of the impact event, and help assess the accuracy of experimental predictions of impact face load.