This study aimed to determine the relationship between serum vitamin B level and tension-type headache. The study groups consisted of 75 patients (40 females, 35 males) with headache and a control group of 49 healthy children (25 females, 24 males). Serum vitamin B level < 200 pg/ml was defined as deficient, and < 160 pg/ml as severely deficient. The serum vitamin B level was measured by the electrochemiluminescence (ECLIA) method. The serum vitamin B levels in the headache and control groups were 273.01 ± 76.77 and 316.22 ± 74.53 pg/ml, with the difference determined as statistically significant (p = 0.003). In the case group, 18/75 patients (24%) had a serum vitamin B12 level below the normal of 200 pg/ml, and in the control group 4/49 (8%) patients were also below the normal range (p = 0.021). The serum vitamin B level in the children with tension-type headache was significantly lower than that in the control group. From the results of the study, it was concluded that there may be an association between vitamin B level and tension-type headache. However, further clinical studies are needed.
Aim: Febrile seizures (FS) are among the most common neurological emergencies during childhood and clinically classified into two types, being simple febrile seizures (SFS) and complicated febrile seizures (CFS). The differentiation between FS types is important, in that they are associated with different morbidity and mortality risks and it is based on the clinical characteristics of each seizure, however there is currently no laboratory test that can guide this differentiation. In this study, the relationship between FS types and hemogram parameters was evaluated and potential use of these parameters in differential diagnosis was investigated. Material and Methods: This retrospective study included a total of 133 patients whose first FS met the criteria of an FS, and whose hemogram results were available. The American Academy of Pediatrics criteria were used to confirm the diagnosis. The patients were divided into two groups as SFS and CFS. Results: Hemoglobin (Hb), hematocrit (HCT), mean platelet volume (MPV), neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) differed significantly between two groups (p<0.001, p=0.002, p=0.033, p<0.001, p<0.001, respectively), while no significant difference was identified in total blood count parameters. Moreover, MPV was significantly higher in CFS group than in SFS group. Conclusion: This is one of the few studies investigating the potential relationship between hemogram parameters and FS types in children. We believe that, although they do not ensure a clear differentiation, Hb, MPV, NLR and PLR may be useful to clinicians in differentiating between FS types, particularly in patients with an unclear seizure history.
The novel coronavirus disease (2019-nCoV, COVID-19) was first reported in China in late 2019. It has impacted the world in a short time and characterized as a pandemic. The clinical picture in children is milder than adults and prognosis are good in children. The diagnosis is made by a real-time polymerase chain reaction test. There is no specific laboratory test for COVID-19 infection in children. The disease progresses more severely in children with an underlying condition and immunocompromised children. There are currently no sufficient and conclusive data on treatment for COVID-19 infection in children. This review aims to present the epidemiology, clinical picture, diagnosis, treatment approaches, and possible preventive measures of COVID-19 disease in children in light of the current literature.
Supernumerary nostril is an extremely rare congenital anomaly. It can be unilateral or bilateral and it sometimes occurs in association with other congenital abnormalities. We describe a newborn infant with bilateral supernumerary nostrils together with oesophageal atresia and patent ductus arteriosus, an association that has not been reported previously in the literature.
Amaç: Demir, çinko ve A vitamini toplum sağlığı açısından önemli mikrobesinlerdir. Bu üç mikrobesin organizmada hücre bölünme ve farklılaşmasında, immünitede, kemik gelişiminde, görme, zeka ve algılama fonksiyonunda, anne ve çocuk mortalitesinde etkilidir. Çalışmada, sağlıklı çocuklarda serum demir, çinko ve A vitamini eksikliği prevalansını ve eksikliklerinin birbiriyle olan ilişkisini araştırdık.Gereç ve Yöntemler: Çalışmamızda Bülent Ecevit Üniversitesi Tıp Fakültesi Genel Çocuk Polikliniği'ne başvuran 6-14 yaş arasındaki 174 kız, 160 erkek olmak üzere toplam 334 sağlıklı çocukta serum demir, çinko, A vitamini değerleri ve tam kan sayımı çalışıldı.Bulgular: Demir eksikliği prevalansı %49.7, çinko eksikliği prevalansı %18.9, A vitamini eksikliği prevalansı %14.7 saptandı. Serum demir, çinko ve A vitamini düzeyleri arasında istatistiksel olarak anlamlı ilişki saptanmadı. Demir eksikliği olan ve olmayan olgular arasında çinko veya A vitamini eksikliği açısından istatistiksel olarak anlamlı fark saptanmadı. Kızlar ve erkekler arasında demir ve A vitamini eksikliği açısından istatistiksel olarak anlamlı fark saptanmadı. Çinko eksikliği ise kızlarda %23.6 (n=41), erkeklerde %13.8 (n=22) olarak bulunmuş olup aradaki fark istatistiksel olarak anlamlı saptandı (p=0.022).Sonuç: Sağlam çocuklarda bile demir, çinko ve A vitamini eksikliğinin önemli boyutlarda olduğu görülmektedir. Özellikle demir eksiliği yürütülen çalışmalara, programlara rağmen halen yüksek oranlarda seyretmektedir. Türkiye'de mikrobesin eksikliklerin sıklığının belirlenebilmesi için yeterli olgu sayısı ile değişik özellikte toplum örneklerinin incelenmesine ihtiyaç vardır.
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