Lipoma is a benign soft tissue tumour of mature adepose tissue and are observed as slow growing, painless, and asymptomatic masses. Occurrance in the submandibular space is relatively rare. We report a case of an unusually huge and plunging fibrolipoma of the floor of the mouth and submandibular space. We report a 52 years old housewife with complaint of progressive painless swelling of the floor of the mouth and submandibular space with interference to speech and mastication for 3years. Clinical examination revealed an 8cm mobile lobulated mass in the floor of the mouth and plunging into the left submandibular space with no ulceration or signs of inflammation on the overlaying mucosa. A needle aspirate of the mass yielded no fluid. Ultrasonography revealed a lobulated extra-oral mass. The lesion was subsequently excised under general anesthesia and histopathological analysis of the tissue showed lobules of mature adipocytes admixed with fibrous tissues, which confirmed the diagnosis. Fibrolipoma of the floor of the mouth and submandibular space is an uncommon tumour with good prognosis. Complete surgical excision is the treatment of choice. Histopathological examination of the tissue must be performed to confirm diagnosis.
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