Chronic bone and soft tissue suppurations have become more frequent recently due to the increasing number of high-energy injuries. There are certain antibiotic beads available for local administration, but they cannot always be applied specifically against the pyogenic microorganisms. In the present study, a new technique of local antibiotic therapy for the treatment of infections is described. Polymethylmethacrylate (PMMA) capsules were produced and filled with 0.1 ml Tazocin (0.02 g piperacillin sodium + 0.005 g tazobactam). The efficacy of these Tazocin-filled capsules was examined in vivo using a rabbit osteomyelitis model. Chronic osteomyelitis was induced in rabbit tibia by local injection of Staphylococcus aureus. The treatment included surgical debridement and implantation of Tazocin-containing PMMA capsules into the medullar cavity (n = 12). Simple surgical debridement with no antibiotic implantation was performed in control animals (n = 7). Results were evaluated using microbiological, radiological and histological methods 14 weeks after induction of osteomyelitis. Eight weeks after the implantation of PMMA capsules, complete physical, radiological and histological healing was achieved in 7 animals, initiation of the reparative phase was observed histologically in 3 cases and no reparative signs were detected in 2 rabbits. In the control group, no significant sign of reparation could be seen in any of the cases.
PURPOSE OF THE STUDYThe treatment of recurrent patellofemoral instability has undergone a paradigm change during the last 15 years. Instead of non-anatomical operations, the current concept favors the reconstruction of injured structures and the normalization of the biomechanical environment. Our aim was to briefly summarize the etiology, diagnostic regimen, and therapeutic decision making of this varied patient group and to review our own patients who underwent combined medial patellofemoral ligament reconstrucion and tibial tubercle transfer. MATERIAL AND METHODSBetween 2015-2017 we performed combined ligament reconstruction and tubercle transfer for recurrent patellofemoral instability on 10 patients. The patients were examined for the degree of trochlea dysplasia, height of the patella, tibial tubercle trochlear groove distance. Additional intraarticular abnormalities were noted. The patients were assessed preoperatively and at follow-up using the Tegner Activity Scale and the Kujala score. Return to sports was also examined. RESULTSThe average age of our patients was 22 years (15-40). We had 6 female patients and 4 male patient. The average followup time was 29 months (12-44). 9 patients had a medializing of the tibial tubercle, whilst one patient had a pure distalization to go along with the medial patellofemoral ligament reconstruction using PEEK tenodesis screws. We had no redislocations up to the last follow-up and patients were able to return to their previous activity level and/or sporting activity. The Kujala score improved from an average preoperative value of 48.9 (32-58) to an average follow-up value of 88.6 (70-97). DISCUSSIONThe essential steps in the treatment of recurrent patellofemoral instability are a thorough physical examination, appropriate imaging and the individual correction of the uncovered anatomical abnormalities. Neither isolated lateral retinacular release, nor medial capsular reefing can preictably produce satisfactory results. CONCLUSIONSMedial patellofemoral ligament reconstruction with tibial tubercle transfer (medializing and/or distalization) is a reliable surgical technique, that provides long term patellar stabilty in this selected group of young patients.
Background: This study aimed at making local antibiotic therapy wider in cases of chronic suppurations by administering antibiotics which previously could not be given in this way through the conventional polymethylmetacrylate (PMMA) carrier techniques. Capsules from this material were produced with a pressing machine designed and laid out by us. The characteristics of antibiotic penetration from this novel carrier were compared to those of PMMA beads. Methods: The time-dependent outflow of amikacin, clindamycin, pefloxacin, piperacillin + tazobactam, amoxicillin + clavulanic acid and cefotaxime was examined from the capsules and the beads with standard microbiological techniques using the Micrococcus luteus ATCC9341 test strain. The diameter of the inhibitory zones was measured after 24 h incubation at 37°C and converted to µg/ml antibiotic concentrations. Results and Conclusions: Our results revealed that all antibiotics showed longer-lasting and higher concentration outflow from the PMMA capsules than from the beads. Therefore, these capsules can provide a more promising new opportunity for specific local antimicrobial treatment in cases of chronic suppurative bone and soft tissue injuries. In these cases the polymerization has already been completed and the heat does not influence the structure of the antibiotics; therefore, it can be inserted into the capsules in powder or solution form.
Medial collateral ligament injury of the first metatarsophalangeal (MTP) joint is rare. If it is missed, chronic instability and traumatic hallux valgus develop, requiring surgical treatment. Different methods have been reported in the limited available literature aiming to restore the balance between the lateral and medial stabilizers by tightening the medial joint capsule with or without additional tendon graft. Our described method utilizes a suture button device (Mini TightRope, Arthrex, Naples, Florida) for reconstruction. This device applies tension to hold the hallux in the correct position, providing stability. Relevant diagnostic regimen, surgical technique, and postoperative care are described, along with a case of a handball player who underwent this procedure. He continues to perform at the same level 38 months postoperatively. Mini TightRope fixation for chronic medial first MTP instability has not been reported. It does not require postoperative immobilization and allows faster return to sport, so it seems superior to other methods when treating athletes.
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