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The ideal wound dressing should achieve rapid healing with hemostasis, antimicrobial activity, maintenance of a moist wound bed, etc. The electrospun blend mat meets the requirements outlined for wound healing, by their microfibrous structures providing a suitable environment for wound healing. In this study, a duallayer nanofiber blend mat wound dressing of nitrofurazone (NFZ)-loaded poly(L-lactide) (PLLA)/sericin nanofibers and NFZ-loaded PLLA nanofibers is fabricated by electrospinning. The NFZ-loaded PLLA/ sericin nanofibers act as the first layer and then the NFZ-loaded PLLA nanofibers are the second layer to prepare the dual-layer fiber dressings. The prepared dual-layer NFZ-loaded fiber dressings have satisfactory antibacterial activity against both Gram-positive and Gram-negative bacteria. In vitro drug release studies show that the drug release profiles can be controlled by adjusting the drug amount in different layers of the dual-layer dressings. The methyl thiazolyl tetrazolium (MTT) assays demonstrate that the NFZ-loaded PLLA/sericin fibers are nontoxic and biocompatible. In vivo wound healing tests are performed in rats. The results reveal that the dual-layer fiber dressings perform better than commercial non-woven dressing in decreasing wound size. It is observed at 12 days that the wound size reduction is 97% for being dressed with the dual-layer fiber dressings but 84% for the commercial woven dressing.These NFZ-loaded PLLA/sericinkPLLA dual-layer fiber mats may provide a promising candidate for accelerating wound healing.

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V 2 O 5 -doped a-Fe 2 O 3 composite nanotubes have been successfully fabricated via a simple one-step electrospinning technique followed by calcination treatment. For the first time, we found that the magnetic properties of the as-prepared samples were significantly dependent on the contents of the dopant. In comparison with pristine a-Fe 2 O 3 , perfect reversibility, more excellent capacitance and better cycling stability were simultaneously observed for the hybrid metal oxide with an appropriate mass ratio of V 2 O 5 (VFNT1) when it was utilized for supercapacitor electrodes, indicating that the doped a-Fe 2 O 3 tubular nanostructures are fairly promising for practical applications not only in magnetic recording but also in the energy storage field.

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has a direct bandgap of 1.8 eV due to the 2D structure. [ 11 ] This unique feature brings few layer MoS 2 signifi cant improvement in optical, electronic, and mechanical properties. And the few layer MoS 2 nanosheets have been attracted great interest and applications in catalysis, [ 12 ] phototransistors, [ 13 ] solar cells, [ 14 ] lithium ion batteries, [ 15 ] electrocapacitor, [ 16 ] and fi eld emission, [ 17 ] etc. Polypyrrole (PPy) is one of the most frequently studied conducting polymers in the past few decades due to its high conductivity, high storage ability, good thermal and environmental stability, high redox and capacitive current, and excellent biocompatibility. [ 18 ] Furthermore, the synthesis and purifi cation of PPy are relatively easy. It has been reported that PPy and its derivatives could be synthesized through both chemical and electrochemical polymerization approaches in either organic or aqueous acid media. [ 19 ] Recently, PPy nanoparticles have been reported to exhibit intrinsic peroxidase-like activity, which could be employed for quantitative detection of H 2 O 2 generated by macrophages. [ 20 ] In addition, PPy and other types of conducting polymers have also be found to participate in the peroxidase-like reaction and enhance the catalytic performance. [ 21 ] In this work, we for the fi rst time prepared algae-like MoS 2 / PPy nanocomposite in a one-pot reaction. The MoS 2 /PPy nanocomposite was prepared using a hydrothermal route to have direct oxidation polymerization of pyrrole in the presence of ammonium tetrathiomolybdate, which of the obtained PPy could in situ well-distributed grown on the surface of MoS 2 sheets. We also show the peroxidase-like activity of MoS 2 /PPy nanocomposite toward the oxidation of peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H 2 O 2 to produce a blue color. In addition, a comparative catalytic activity has been made with that of the independent MoS 2 and PPy nanomaterial, which revealed that the synergistic coupling effect between few layer MoS 2 nanosheets and PPy component contributed the enhanced catalytic activities.

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