α7nAChR was ubiquitously expressed by CD4(+)T lymphocytes, which was correlated with the cell activation status. Meanwhile, activation of nAChRα7 by nicotine in CD4 cells reduced the Th17 response.
Rare cases of CML present with monocytosis as well as morphologic dysplasia and harbor p210 BCR-ABL1 . Cytogenetic and molecular studies must be performed to confirm the diagnosis of this kind of CML.
K E Y W O R D Schronic myeloid leukemia, monocytosis, p210 BCR-ABL
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