An efficient solvent-free synthesis of β-CF3-substituted phosphonates and phosphine oxides via hydrophosphonylation and hydrophosphinylation of α-CF3 styrenes with H-phosphonates and H-phosphine oxides was developed.
A novel and facile method for the synthesis of N-β-CF 3 -substituted 2-pyridones via hydroamination of α-(trifluoromethyl)styrenes with 2-pyridones was described. The reaction proceeded smoothly at room temperature, affording a variety of N-(β-trifluoromethyl-β-arylethyl)pyridin-2(1H)ones in moderate to good yields with excellent N-regioselectivity.
Dunhuang murals are abundant in art. Tiger is a vital animal element. It is well represented in the design of cultural and creative products. Tiger elements on the murals not only possess the nature of the tiger totem in Chinese traditional culture but also have a profound religious connotation and convey unique artistic characteristics. The paper takes the tiger elements in part of the murals in Dunhuang as the staring poing, focuses on the cultural connotation of tiger elements in Dunhuang murals. Data collection was conducted to grasp the sales of cultural and creative products. Moreover, a questionnaire survey was made to grasp the deficiencies of cultural and creative products and consumers' opinions. Finally, suggestions for the design, marketing, and cultural re-creation of Dunhuang tiger elements were proposed as a research result. The result has contributed to enriching the research contents in the field of Dunhuang cultural creation and providing new ideas and methods for designing Dunhuang cultural creation products.
A simple and straightforward addition or defluorination of α-(trifluoromethyl)styrenes with 2-nitroimino-imidazolidine (2a), 2-(nitromethylene)imidazolidine (2b), 2-cyanoimino-thiazolidine (2c), and (E)-1-methyl-2-nitroguanidine (2d), in a controlled manner, was developed. The hydroamination of α-(trifluoromethyl)styrenes with 2a, 2b, 2c, and 2d was completed in the presence of DBN at room temperature within 0.5–6 h, affording structurally diverse β-trifluoromethyl-β-arylethyl analogues of neonicotinoids in moderate to good yields. The γ,γ-difluoro-β-arylallyl analogues of neonicotinoids were also successfully synthesized via defluorination of α-(trifluoromethyl)styrenes, with 2a and 2c using NaH as base at an elevated temperature together with a prolonged reaction time of 12 h. The method features simple reaction setup, mild reaction conditions, broad substrate scope, high functional group compatibility, and easy scalability.
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