Introduction:
Benign fibrous histiocytoma (BFH) is a mesenchymal tumor composed of fibroblasts and histiocytes, which normally occurs in the bone tissue and/or the skin of the limbs. BFH of the nasal septum is rare worldwide.
Patient concerns:
A 38-year-old female patient attended our clinic with congestion in her right nasal cavity.
Diagnoses:
Endoscopic examination revealed a mass within the right nasal passage. Immunohistochemical staining demonstrated cells labeled with VIM (+), CD68PGM1 (+), CD34 (–), Actin (–), PCK (–), EMA (–), Desmin (–), SMA (–), S-100 (–), P63 (–), ALK-1 (–), beta-catenia (+), and KI67 (+). Clinical and histopathological examinations showed that the mass was a septum-originated BFH.
Interventions:
For the treatment of BFH of the nasal septum, the mass was removed endoscopically using a transnasal approach.
Outcomes:
No recurrence was observed over 30 months of follow-up.
Conclusion:
To prevent the recurrence wide local resection with histological clear margin and long-term follow-up with an endoscope are necessary.
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