Chinese medicines (CMs) are being used more and more widely throughout the world. Since there are many poisoning incidents caused by misuse or confusion of CMs, their safe use has become a critical issue internationally. In this paper, based on the investigation of the current market of CMs, reasons for various confusions of Chinese Materia Medica (CMM) are analyzed and clarified, such as herbs with multiple sources, regional custom-herbs, confusion in nomenclature, similarity in appearance, and complexity of processed products. Authentication of plant material is critical to the safe and effective use of CMM. In this paper, several authentication methods, such as taxonomy, morphology, microscopy, physical and chemical authentication, DNA molecular biology and their advanced applications in this area, are introduced. Furthermore, it is proposed that an authority on the authentication of CMM be established, as a physical institution and/or as an electronic database.
This review describes the histories, common medicinal plant species, their processing methods and therapeutic applications in Ayurveda and TCM. The insights provided through this article may be used by herbal drug researchers and pharmacologists for further exploration of botanical drugs from these two traditional systems of medicine.
BackgroundRadix Polygoni Multiflori is the dried root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae). According to Chinese medicine theory, raw (R-RPM) and processed (P-RPM) Radix Polygoni Multiflori possess different properties. The present study investigates the differences in chemistry between raw and processed Radix Polygoni Multiflori.MethodsFive pairs of R-RPM and P-RPM as well as 15 commercial decoction pieces were analyzed with high performance liquid chromatography (HPLC) and mass spectrometry (MS).ResultsTwo anthraquinones, namely emodin-8-O-(6'-O-malonyl)-glucoside and physcion-8-O-(6'-O-malonyl)-glucoside disappeared or decreased significantly and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside, emodin-8-O-β-D-glucopyranoside and physcion-8-O-β-D-glucopyranoside decreased after the R-RPM samples being processed. On the other hand, the contents of emodin and physcion generally increased after processing.ConclusionThe present study indicates that processing Radix Polygoni Multiflori may change the contents and types of chemicals in it. These changes are probably responsible for the various pharmacological effects of R-RPM and P-RPM as well as hepatotoxicity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.