The ongoing Covid-19 pandemic has focused our attention on airborne droplet transmission.
In this study, we simulate the dispersion of cough droplets in a tropical outdoor
environment, accounting for the effects of non-volatile components on droplet evaporation.
The effects of relative humidity, wind speed, and social distancing on evaporative droplet
transport are investigated. Transmission risks are evaluated based on SARS-CoV-2 viral
deposition on a person standing 1 m or 2 m away from the cougher. Our results show that
the travel distance for a 100
µ
m droplet can be up to 6.6 m under a wind
speed of 2 m/s. This can be further increased under dry conditions. We found that the
travel distance of a small droplet is relatively insensitive to relative humidity. For a
millimetric droplet, the projected distance can be more than 1 m, even in still air.
Significantly greater droplets and viral deposition are found on a body 1 m away from a
cougher, compared to 2 m. Despite low inhalation exposure based on a single cough,
infection risks may still manifest through successive coughs or higher viral loadings.
In our study, BMI was moderately correlated with pulmonary function positively and exacerbations negatively. To some extent, BMI might be a useful indicator to predict the prognosis of COPD patients and for long-term management.
Microfluidics has been undergoing fast development in the past two decades due to its promising applications in biotechnology, medicine, and chemistry. Towards these applications, enhancing concentration sensitivity and detection resolution are indispensable to meet the detection limits because of the dilute sample concentrations, ultra-small sample volumes and short detection lengths in microfluidic devices. A variety of microfluidic techniques for concentrating analytes have been developed. This article presents an overview of analyte concentration techniques in microfluidics. We focus on discussing the physical mechanism of each concentration technique with its representative advancements and applications. Finally, the article is concluded by highlighting and discussing advantages and disadvantages of the reviewed techniques.
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