Purpose: The purpose of this study is to investigate the feasibility of increasing the system spatial resolution and scanning speed of Hologic Selenia Dimensions digital breast tomosynthesis (DBT) scanner by replacing the rotating mammography x-ray tube with a specially designed carbon nanotube (CNT) x-ray source array, which generates all the projection images needed for tomosynthesis reconstruction by electronically activating individual x-ray sources without any mechanical motion. The stationary digital breast tomosynthesis (s-DBT) design aims to (i) increase the system spatial resolution by eliminating image blurring due to x-ray tube motion and (ii) reduce the scanning time. Low spatial resolution and long scanning time are the two main technical limitations of current DBT technology. Methods: A CNT x-ray source array was designed and evaluated against a set of targeted system performance parameters. Simulations were performed to determine the maximum anode heat load at the desired focal spot size and to design the electron focusing optics. Field emission current from CNT cathode was measured for an extended period of time to determine the stable life time of CNT cathode for an expected clinical operation scenario. The source array was manufactured, tested, and integrated with a Selenia scanner. An electronic control unit was developed to interface the source array with the detection system and to scan and regulate x-ray beams. The performance of the s-DBT system was evaluated using physical phantoms. Results: The spatially distributed CNT x-ray source array comprised 31 individually addressable x-ray sources covering a 30 angular span with 1 pitch and an isotropic focal spot size of 0.6 mm at full width at half-maximum. Stable operation at 28 kV(peak) anode voltage and 38 mA tube current was demonstrated with extended lifetime and good source-to-source consistency. For the standard imaging protocol of 15 views over 14, 100 mAs dose, and 2 Â 2 detector binning, the projection resolution along the scanning direction increased of 1.08. The improvement is more pronounced for faster scanning speeds, wider angular coverage, and smaller detector pixel sizes. The scanning speed depends on the detector, the number of views, and the imaging dose. With 240 ms detector readout time, the s-DBT system scanning time is 6.3 s for a 15-view, 100 mAs scan regardless of the angular coverage. The scanning speed can be reduced to less than 4 s when detectors become faster. Initial phantom studies showed good quality reconstructed images. Conclusions: A prototype s-DBT scanner has been developed and evaluated by retrofitting the Selenia rotating gantry DBT scanner with a spatially distributed CNT x-ray source array. Preliminary results show that it improves system spatial resolution substantially by eliminating image blur due to x-ray focal spot motion. The scanner speed of s-DBT system is independent of angular coverage and can be increased with faster detector without image degration. The accelerated lifetime measurement demo...
Monte Carlo simulations were used to quantify the amount of scattered radiation a scanning slot detector geometry designed for use in digital mammography. Ratios of the scatter to primary (S/P) x-ray photon energy absorbed in the detector were obtained for a Lucite phantom, and were investigated as a function of photon energy, phantom thickness, and slot detector width. Over a Lucite phantom thickness range of 2-6 cm, the S/P ratios range from about 0.10 to 0.17 for a 4 mm wide slot detector at the x-ray photon energies used in mammography. These ratios increased by a factor of approximately 1.8 when the slot width was increased to 10 mm. In general, 20 keV photons gave S/P ratios similar to those of a 30 kVp x-ray spectrum (Mo target + 30 microns Mo filtration). The use of a 3 cm air gap reduced the S/P ratios by a factor of between 2.5 and 3.4, depending on the phantom thickness. For a constant primary energy fluence, coherent scatter was reduced as photon energy increased, whereas Compton scatter increased with increasing photon energy. With no air gap, the contributions of coherent and Compton scatter were found to be equal at 25 keV, whereas the introduction of a 3 cm air gap resulted in equal contributions for the two scatter processes at 36 keV. A 10 mm wide slot detector consisting of a 36.7 mg/cm2 thick Gd2O2S:Tb phosphor screen was compared to an ideal detector absorbing all incident primary/scatter photons. Average differences in the S/P ratios for these two detectors were 7% with no air gap and approximately 4% with a 3 cm air gap. The results obtained in this study will assist in the design of an optimal slot detector for use in digital mammography.
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