Cation-free zirconosilicate zeolite CHA and thin zirconia-supported membranes were in situ synthesized in a fluoride-free gel for the first time. The usage of the ZrO 2 /Al 2 O 3 composite support inhibited the transportation of aluminum from the support into zeolite membranes. No fluorite source was used for the synthesis of cation-free zeolite CHA membranes, indicating the green property of the synthesis. The thickness of the membrane was only 1.0 μm. The best cation-free zeolite CHA membrane prepared by the green in situ synthesis displayed a high CO 2 permeance of 1.1 × 10 −6 mol/(m 2 s Pa) and CO 2 /CH 4 selectivity of 79 at 298 K and 0.2 MPa pressure drop for an equimolar CO 2 /CH 4 mixture.

Catalytic performance of MoOx–POx supported on oxidized carbon nanotube (oCNT) catalysts for oxidative dehydrogenation of propane has been investigated. The catalysts were characterized by XRD, TEM, and IR spectroscopy techniques and then tested through the propane oxidation dehydrogenation reaction. The results reveal that the addition of MoOx significantly improves the catalytic activity but reduces the selectivity to propene. In contrast, adding POx decreases the reactivity and increases the selectivity by suppressing the combustion reaction. Adding both POx and MoOx can improve the selectivity at the same conversion rate and thus increase the yield of the catalyst. As compared to MoOx/oCNTs, the stability of the MoOx–POx/oCNT catalyst is significantly improved. This is because the addition of POx can promote MoOx dispersion on the CNT surface and hence improve the catalytic performance.

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Brain metastasis is a severe complication that affects the survival of lung cancer patients. However, the mechanism of brain metastasis in lung cancer remains unclear. In this study, we constructed an in vitro BBB model and found that cells from the high-metastatic nonsmall cell lung cancer (NSCLC) cell line H1299 showed a higher capacity to pass through the blood–brain barrier (BBB), as verified by Transwell assays, than cells from the low-metastatic NSCLC cell line A549. Brain microvascular endothelial cells (BMECs) could internalize H1299-derived exosomes, which remarkably promoted A549 cells across the BBB. The BBB-associated exosomal long noncoding RNA (lncRNA) was selected from the RNA-Seq dataset (GSE126548) and verified by real-time PCR and Transwell assays. LncRNA LINC01356 was significantly upregulated in H1299 cells and exosomes derived from these cells compared to that of A549 cells. Moreover, LINC01356 was also upregulated in serum exosomes of patients with NSCLC with brain metastasis compared with those without metastasis. In addition, BMECs treated with LINC01356-deprived exosomes expressed higher junction proteins than those treated with the control exosomes, and silencing LINC01356 in exosomes derived from H1299 cells could inhibit A549 cells from crossing the BBB. These data might indicate that the exosomal lncRNA LINC01356 derived from brain metastatic NSCLC cells plays a key role in remodeling the BBB system, thereby participating in brain metastasis in lung cancer.