Introduction: This study analyzed the effectiveness of 650-nm red-light feeding instruments in the control of myopia.
Methods: In this study, 164 school-aged participants diagnosed with myopia in the city of Shenzhen were enrolled in a red-light feeding instrument study. Of these, 41 were enrolled in the mild-to-moderate myopia group that received red-light feeding (RLMM group), 65 were enrolled in the mild-to-moderate myopia group that received single-vision spectacle treatment (SVSMM group), and 58 were included in the severe-myopia group that received red-light feeding (RLS group).
Results: After the baseline values of the three groups were matched, the right-eye data were used for statistical analysis. The average return-visit time of each group was 60.42 days, and changes in the observation indexes before treatment and after follow-up treatment were compared. As the primary outcome, the axial length changes in the right eye of the SVSMM group (0.08 ± 0.40 mm), the RLMM group (–0.03 ± 0.11 mm), and the RLS group (−0.07 ± 0.11 mm) were compared and showed a statistical result of P < 0.001.
Conclusion: The study results verified that red light had a noticeable effect on the control of myopia and that low-level red-light therapy played a vital role in the treatment of severe myopia.
To explore the relationship between binocular imbalance (BI) and the abnormal development of binocular refraction. BI data were collected by enrolling the first 1,000 adolescents and children aged 6–18 years in Shenzhen Eye Hospital from April 2020 to January 2021. In this cross-sectional study, the imbalance value (IV) did not show a statistical correlation with the spherical equivalent (SE) (oculus dexter [OD]:
r
= 0.022,
p
= 0.586; oculus sinister [OS]:
r
= −0.021,
p
= 0.606), and had little correlation with the uncorrected visual acuity (VA) (OD:
r
= −0.084,
p
= 0.039; OS:
r
= −0.034,
p
= 0.408). The proportion of binocular contrast imbalance (BCI) (the absolute value) maintained the highest level (from 54.42 to 79.17 percent) with the increase of bilateral SE difference in the four subcategories (binocular balance, monocular suppression, binocular rivalry, and BCI). From −100 to +100 of IV, the SE of the left eye tends to increase negatively when compared with the right eye (from −95 < IV ≦ −80, SE difference = −0.83 ± 1.58, to −20 < IV ≦ −10, SE difference = −0.14 ± 0.61; from 10 ≦ IV <20, SE difference = −0.05 ± 0.80, to 80 ≦ IV <95, SE difference = 1.48 ± 2.77). BI widely exists within the general pediatric population. The BI did not show significant correlation with the unilateral eye refractive state and the VA. However, the BI may be accompanied by imbalanced development of the eye refractive system. Furthermore, the SE of the dominant eye (from the prospective of BI) tends to be more negative than that of the opposite eye as the value increases.
Clinical Trial Registration number: ChiCTR2100045457.
Purpose. To study the influence of parents’ educational backgrounds and understanding on the progress of myopia in their offspring. Methods. Spherical equivalent refraction (SE) of the children (aged 6–14) in China was assessed with cycloplegic autorefraction in a two-year longitudinal study. The parents’ background information and myopia-related cognition were collected by questionnaires. Results. The offspring of parents with lower education and more myopic SE had higher myopic progression (mean = –1.42 ± 1.06) than the children of other groups (
P
<
0.05
). The parents’ understanding of the proper outdoor activity time, sleep duration, reading distance, and indoor illumination for children was not significantly correlated with the progression of myopia in their offspring. The parent’s preference for eye care visit frequency had a significant correlation with the myopia development of their children (r = 0.076,
P
=
0.001
∗
). The mean SE progression was −0.84 ± 1.37 and −0.58 ± 1.29 in the children whose parents considered that extracurricular classes would negatively affect myopia development progression and the children whose parents believed it would not, respectively (
P
=
0.026
∗
). Conclusions. Most parents misunderstand the influence of insufficient outdoor sports time and extracurricular classes, which require extra near-vision work. Besides, for parents with low educational background and more myopic SE, their offspring had higher myopia progression and may be the key group for myopia control. Finally, parents may obtain life advice and knowledge related to preventing myopia after their children become myopic. It may be of positive significance if this process could take place before myopia onset.
Orthokeratology is currently known as one of the most effective methods of myopia control in the process of rapid deterioration of the global myopia prevalence. As orthokeratology is widely used, it is necessary to evaluate its complications reasonably and accurately. Eye surface problems in children, such as dry eyes, have received increasing attention. At present, there is no conclusive evidence on how orthokeratology affects the ocular surface, especially the tears. To our knowledge, this is the first study to explore the relationship between orthokeratology lenses and tears through meta-analysis. However, it is still challenging to get a convincing conclusion and a higher level of evidence in this meta-analysis. Reasons for this include limitation of study design, lack of clarity on important confounding factors, lack of appropriate statistical tools, and other biases. This paper will analyze the dilemma existing in the current research from different perspectives to provide meaningful information for future studies in this field.
The retinal pigment epithelium (RPE), as a single layer of cells that performs multiple functions posterior to the eye, is a promising target site for the prevention and treatment of...
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