The Zhaoshan long-baseline Atom Interferometer Gravitation Antenna (ZAIGA) is a new type of underground laser-linked interferometer facility, and is currently under construction. It is in the 200-meter-on-average underground of a mountain named Zhaoshan which is about 80 km southeast to Wuhan. ZAIGA will be equipped with long-baseline atom interferometers, high-precision atom clocks, and large-scale gyros. ZAIGA facility will take an equilateral triangle configuration with two 1-km-apart atom interferometers in each arm, a 300-meter vertical tunnel with atom fountain and atom clocks mounted, and a tracking-and-ranging 1-km-arm-length prototype with lattice optical clocks linked by locked lasers. The ZAIGA facility will be used for experimental research on gravitation and related problems including gravitational wave detection, high-precision test of the equivalence principle of micro-particles, clock based gravitational red-shift measurement, rotation measurement and gravito-magnetic effect. arXiv:1903.09288v4 [physics.atom-ph]

Numerous animal studies have demonstrated that fear acquisition and expression rely on the coordinated activity of medial prefrontal cortex (mPFC) and amygdala and that theta oscillations support interregional communication within the fear network. However, it remains unclear whether these results can be generalized to fear learning in humans. We addressed this question using intracranial electroencephalography recordings in 13 patients with epilepsy during a fear conditioning paradigm. We observed increased power and inter-regional synchronization of amygdala and mPFC in theta (4 to 8 hertz) oscillations for conditioned stimulus (CS+) versus CS−. Analysis of information flow revealed that the dorsal mPFC (dmPFC) led amygdala activity in theta oscillations. Last, a computational model showed that trial-by-trial changes in amygdala theta oscillations predicted the model-based associability (i.e., learning rate). This study provides compelling evidence that theta oscillations within and between amygdala, ventral mPFC, and dmPFC constitute a general mechanism of fear learning across species.

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Object: Subdural or deep intracerebral electrodes are essential in order to precisely localize epileptic zone in patients with medically intractable epilepsy. Precise localization of the implanted electrodes is critical to clinical diagnosing and treatment as well as for scientific studies. In this study, we sought to automatically and precisely extract intracranial electrodes using pre-operative MRI and post-operative CT images.Method: The subdural and depth intracranial electrodes were readily detected using clustering-based segmentation. Depth electrodes were tracked by fitting a quadratic curve to account for potential bending during the neurosurgery. The identified electrodes can be manipulated using a graphic interface and labeled to cortical areas in individual native space based on anatomical parcellation and displayed in the volume and surface space.Results: The electrodes' localizations were validated with high precision. The electrode coordinates were normalized to a standard space. Moreover, the probabilistic value being to a specific area or a functional network was provided.Conclusions: We developed an integrative toolbox to reconstruct and label the intracranial electrodes implanted in the patients with medically intractable epilepsy. This toolbox provided a convenient way to allow inter-subject comparisons and relation of intracranial EEG findings to the larger body of neuroimaging literature.