Distribution of HBV, HCV and HIV results of the inpatients or outpatients, who had been treated for various diagnoses in Diyarbakır Training and Research Hospital between 2005 and 2012, among years was investigated.Files of the patients, who had been treated as inpatient or outpatient 992. to any diagnosis between 01/01/2005 and 31/12/2012 in the clinics or policlinics of Diyarbakır 581 due Training and Research Hospital, were retrospectively reviewed using patient file database. Serum samples (235.534 for HBsAg, 196.727 for Anti-HBs antibody, 98.497 for HBeAg, 97.417 for Anti-HBe antibody, 225.483 for HCV and 138.923 for HIV) of these patients, which had been processed in microbiology laboratory, were studied by chemiluminescence technique using Roche E-170 (Modular Analytics System) device.Prevalence rates between 2005 and 2012 were as follows: 15.9%-9% for HBsAg, 32.9%-52.3% for Anti-HBs, 2.5%-1.8% for HBeAg, 30.4%-25.2% for Anti-HBe, 1%-0.7% for Anti-HCV, and 0.1%-1% for Anti-HIV. Increase in Anti-HBs prevalence is the successful outcome of routine immunization in population. This suggests that, governmental policies focused on this subject have resulted in successful outcomes and that people also take care about this.A prevalence rate decreasing to 9% from 15.9% for HBsAg and prevalence rate increasing to 52.3% from 32.9% for Anti-HBs antibody positivity in 8-year period in our region is quite meaningful. Such favorable developments in our region are of great valuable in terms of indicating to what extent could struggle against HBV is controlled by education and awareness.
ÖZ Comamonas türleri, diğer Pseudomonas grubunun çok sayıdaki cins ve türünden biridir. Comamonas türlerinden Comamonas testosteroni immün yetmezlikli kişilerde ender olarak enfeksiyonlara yol açan bir türdür. C. testosteroni'nin nötropeni öyküsü olan immün sistemi baskılanmış hastalarda bakteriyemi etkeni olabileceğini vurgulamak ve suşun antibiyotik duyarlılığını belirlemek amacıyla olgumuz sunulmuştur. Hematoloji kliniğinde lökopeni nedeniyle yatırılan 30 yaşındaki kadın hastanın laboratuvarımıza gönderilen kan kültür örneği, BD Bactec 9120 (Becton Dickinson, ABD) otomatize kan kültürü cihazına yüklenmiştir. Kan kültürlerinde üreyen Gram negatif basil görünümünde, katalaz ve oksidaz pozitif koloniler "VITEK-2 Compact" (bioMérieux, Fransa) otomatik identifikasyon cihazına yüklenmiştir. C. testosteroni olarak tanımlanan suş, Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi Mikrobiyoloji Laboratuvarı'na doğrulama amacıyla gönderilerek bu merkezde Matrixassisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) (Bruker Daltonics, Bremen, Almanya) kütle spektrometre yöntemi ile doğrulanmıştır. Spontan abortus nedeniyle bağışıklık sistemi zayıflamış olan lökopenili olgumuzda üreyen C. testosteroni'nin antibiyotik duyarlılık paterninin belirlenmesi amaçlanmıştır. Buna göre ampisiline orta duyarlı bulunan C. testosteroni, amoksisilin/klavulanik asit, piperasilin/tazobaktam, sefuroksim, sefoksitin, sefoperazon/sulbaktam, trimetoprim/sulfametaksazol, amikasin, gentamisin, siprofloksasin, fosfomisin, imipenem ve meropeneme duyarlı fakat Sefiksim ve seftazidime dirençli bulunmuştur. Anahtar kelimeler: Comamonas testosteroni, kan kültürü, bakteriyemi ABSTRACT An Uncommon Cause of Bacteremia: Comamonas testosteroni
İ İd dr ra ar r Ö Ör rn ne ek kl le er ri in nd de en n İ İz zo ol le e E Ed di il le en n E Es sc ch he er ri ic ch hi ia a C Co ol li i S Su uş şl la ar rı ın nı ın n Ç Çe eş şi it tl li i A An nt ti im mi ik kr ro ob bi iy ya al ll le er re e D Di ir re en nç ç O Or ra an nı ı R Re es si is st ta an nc ce e R Ra at te es s A Ag ga ai in ns st t V Va ar ri io ou us s A An nt ti im mi ic cr ro ob bi ia al ls s i in n E Es sc ch he er ri ic ch hi ia a C Co ol li i S St tr ra ai in ns s I Is so ol la at te ed d f fr ro om m U Ur ri in ne e S Sa am mp pl le es s
Anahtar kelimeler: İmmünsüpresyon, bakteriyemi, Listeria monocytogenes ABSTRACT A Rarely Isolated Pathogen: Listeria monocytogenes Listeria monocytogenes is usually a zoonotic infectious agent. It is an important pathogen that may cause infection in the elderly or in immunocompromised patients with predisposing conditions. The present case is presented to underline the necessity of keeping in mind that L. monocytogenes can be the cause of bacteremia in geriatric and immunocompromised patients. An 89-yearold patient, who was diagnosed as iron deficiency anemia four months before hospitalization, was hospitalized in the Internal Medicine Clinic and his blood samples were transferred to our laboratory for blood culture. Growth of catalase-positive, oxidase-negative gram-positive bacteria in the morphology of coccobacillus was observed in the blood c u l t u re . T h e i s o l a t e d s t r a i n w a s i d e n t i f i e d as L. monocytogenes using the conventional methods and the automated system (VITEK 2, bioMérieux, France). The strain identified as L. monocytogenes by device was transferred to the Marmara University Pendik Training and Research Hospital Microbiology Laboratory and the bacterial identification was confirmed at the species level using Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) (Bruker Daltonics, Bremen, Germany)
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