A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion. The patient was operated on. The pathological diagnosis was reported as papillary thyroid carcinoma. The immunohistochemical examination showed multiple foci of Langerhans cell histiocytosis involving both lobes. The patient died due to cardiac arrest with respiratory causes in the early postoperative period. Langerhans cell histiocytosis is a rare primary condition which involves abnormal clonal proliferation of Langerhans cells in various tissues and organs. Thyroid involvement is infrequently seen. Although the etiology is unknown, genetic components may be linked to the disease. It is also associated with a family history of thyroid disease. Papillary thyroid carcinoma is the most common malignant epithelial tumor of the thyroid gland. Langerhans cell histiocytosis presenting with papillary thyroid carcinoma is rare. The privilege of our case is langerhans cell histiocytosis of the thyroid with multiple cervical lymph node involvement accompanying cervical lymph node metastatic thyroid papillary carcinoma.

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ntestinal nematodlar, özellikle çocukluk çağı hastalıkları olarak karşı-mıza çıkar. Gelişmiş ülkeler de dâhil tüm dünyada yaygın olarak görü-lürler. Genellikle semptomatik olmadıkları için ameliyat sırasında tesadüfen veya otopsi serilerinde tanı alırlar. Ovaryan veya endometriyal enfeksiyon genellikle intraperitoneal yaygın hastalık sonrası görülür. Tüm kadın genital yolu boyunca tutulum olabilmektedir. A An na ah ht ta ar r K Ke el li im me el le er r: : Nematod enfeksiyonları; parazitik hastalıklar; over kistleri A AB BS ST TR RA AC CT T Parasitic infection of the female genital tract is extremely important in terms of the consequences. In case of no response to treatment of pelvik inflamatory disease and tubo-ovarian abcess, a parasitic infection's appropriate treatment should be kept in mind. A mass was spotted on the right pelvic side of a patient presented in this particular case. All tumor markers were in normal range except CA 19,9. The laparoscopic(L/S) approach was chosen as surgical technique and a right adnexectomy was performed. During L/S a wide adhesion site was observed between the anterior abdominal wall and the pfannenstiel incision region. Frozen section revealed a benign cystic lesion. Parasitic infection should be kept in mind in case of adnexial masses. Our patient was in postmenopausal state with no fertility desire. Furthermore this infection might be seen among the young population and might cause fertility problems.

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Objective: Trichoblastomas are rare benign tumors of the skin appendages with epithelial and mesenchymal components that exhibit differentiation to the follicular germinative epithelium and particularly to the follicular stroma of the skin. Our aim was to contribute to already limited literature data in order to gain more insights into the treatment and follow-up of patients with this condition.

Objective:Studies have been performed on many biomolecules to determine the prognosis of LSCC and predict the course of the disease. However, a molecular marker that can be used clinically has not yet been found. Therefore, in this study, we aimed to investigate the expression levels of LRIG 1 in laryngeal cancer. Materials and Methods: In our study, 219 cases who underwent surgery due to LSCC and 88 randomly selected patients whose pathologic result were benign and premalignant lesions in Marmara University Pendik Education and Research Hospital between 2003 and 2018 were analyzed. Patients' data were obtained from the medical records. The tissue microarray method was used to evaluate specimens. Results: There was a statistically significant difference between the tumor differentiation, diagnosis, and the expression of LRIG1 (respectively p=0.045, p<0.001). Also, an increase in the degree of dysplasia in premalignant lesions correlates with a decrease in LRIG1 expression (p=0.015). Conclusion: Our findings suggest that LRIG1 plays a role in the early tumorigenesis of LSCC. Therefore, LRIG1 can be a target molecule for treatment approaches. However, LRIG1 was not correlated with overall survival of the LSCC.