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BackgroundPlatelet rich plasma (PRP) therapy is widely used in enhancing the recovery of skeletal muscle from injury. However, the impact of intramuscular delivery of PRP on hematologic and biochemical responses has not been fully elucidated in exercise-induced muscle damage. The purpose of this investigation the effects of intramuscular delivery of PRP on hematologic and biochemical responses and recovery strategy muscle damage induced by high intensity muscle exercise (exercise-induced muscle damage, EIMD).MethodsModerately active male volunteers participated in this study and were assigned to a control group (control, n = 6) and PRP administration group (PRP, n = 6). The subjects performed exercise with a load of 80% one repetition maximum (1RM) maximal voluntary contraction of the elbow flexors until point of exhaustion of the non-dominant arm was reached. The arms were treated with saline or autologous PRP post-24 h EIMD. Venous blood samples were obtained in the morning to establish a baseline value and 1–4 days post-exercise and were analyzed for serum ferritin, iron, iron binding capacity (IBC), creatinine kinase (CK), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).ResultsThe baseline levels of plasma iron, ferritin, IBC, CK, LDH, AST, and ALT were similar in both the control and PRP groups. However, 24-h following exercise a significant increase in these parameters was observed in both groups between 1 and 4 days during the recovery period. Interestingly, PRP administration decreased plasma iron levels compared to the control on the second day post-exercise. Plasma IBC increased in PRP group from Days 2 to 4 post-exercise compared to the control group whilst PRP administration had no effect on plasma ferritin, CK, AST, ALT, or LDH.ConclusionAcute exhaustive exercise increased muscle damage markers, including plasma iron, IBC, and ferritin levels, indicating muscle damage induced by exercise. PRP administration improves inflammation by reversing the increase in the iron levels post-exercise without displaying any myotoxicity and may have a role to play in the recovery of exercise-induced muscle damage.

This study aimed to find out whether a wearable strain sensor including thermoplastic polyurethane composite with a multi-walled carbon nanotube network could be a viable alternative to an isokinetic dynamometer for the measurement of knee-extensor muscle strength. For the first time, the voltage-torque and angle–time relations of the sensor were determined to allow a comparison between the angle-dependent torque changes of the dynamometer and the sensor. This comparison suggested that the torque–angle relations of the dynamometer and the sensor did not have the same characteristics. In this regard, the sensor may be used in the torque measurements due to the moderate correlation between the torque values determined via the isokinetic dynamometer and the sensor and due to the significant difference between low and high torque values of the sensor. By the same token, the torque-angle graph of the sensor may be more informative than that of the dynamometer in evaluation of knee problems.

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Dünya, koronavirüs hastalığı [coronavirus disease-2019 (COVID-19)] salgını nedeni ile, hayatı değiştiren olağanüstü bir zorluk yaşıyor. Hayatı zorlaştıran alışkanlıklar, "sosyal mesafe", "evde kal" artık günlük hayatımızın bir parçası olurken, birçok ülke bu yeni normal yaşam alışkanlıklarına alışmaya başlamış durumdadır. 1 COVID-19 salgınının tam olarak ne zaman azalacağını ve toplumların normal işlevlerine geri döneceğini tahmin etmek zordur; bunun gerçekleşmesi biraz zaman alabilir. Şu anda COVID