Beta-thalassemia major (BTM) is one of the most common hereditary hemoglobinopathies in Pakistan, with 9.8 million persons in the general population and gene carriers (5-7%). The mothers of these chronically ill patients often endure many challenges associated with caregiving. Objective: To determine the prevalence of psychological distress experienced by mothers of children suffering from BTM in a developing country. Methods: From March 2022 to August 2022, this descriptive cross-sectional study was done among mothers of thalassemic children who presented to the Outpatient Department of Benazir Bhutto Hospital in Rawalpindi. A self-structured questionnaire consisting of 1) Socio-demographic characteristics and 2) the Kessler-10 (K-10) Distress Measure was used to collect data. To determine the level of psychological distress among mothers of children, a descriptive analysis was done. The Spearman correlation was used to explore the relationship between demographic factors and the level of psychological distress experienced by mothers of children with thalassemia. Results: The mean age of mothers being interviewed was 37.65±3.63 years. Out of 83 mothers, 54 (65.1%) had psychological distress. The children's age (r= -.275) and any psychological support taken by mother (r= -.253) were correlated (p < .05) negatively with the severity of psychological distress. Conclusions: Our study identified that most mothers of children suffering from thalassemia had psychological distress. Thus, these mothers are at risk of poor health outcomes and should be targeted for screening and treatments focused on improving their health and well-being
Background: For renal transplant, a living donor nephrectomy is not without its hazards with a reported mortality rate of 0.02%. The laparoscopic donor nephrectomy (LDN) approach is becoming the standard of care in most centers worldwide. But open donor nephrectomy (ODN) is a viable alternative to the laparoscopic approach. We aimed to establish the fact that reflects the safety of ODN as an alternative when the laparoscopic approach is not available without compromising the expanding demands of donor nephrectomies for renal transplantation. Methods: From June 2017 through June 2019, we performed 56 open donor nephrectomies (ODN) at The Kidney Centre. Data collected on living donors included sex, body mass index (BMI), relationship to the recipient, pre-op and post-op creatinine level, pre-and post-op hemoglobin level, incision type, blood transfusion, any intraoperative complications according to the Clavien-Dindo classification (CDC) of Surgical Complications. Results: Brother was found to be the most frequent relation in our study. Left side ODN was done in 41 cases with an advantage of a longer length of the left renal vein. We did not encounter any significant complications in our study. Conclusion: Open donor nephrectomy is an important safe method to harvest kidneys for renal transplantation. Keywords: ESRD, Open Donor Nephrectomy, LDKT
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