Background: Advances in medical science and success in increasing the survival rate of vulnerable infants have raised the future evolution issues of these children. Developmental and behavioral disorders are the most common problem in children after discharge from NICU. A lot of factors are involved in the occurrence of developmental disorders. Objectives: According to the importance of the subject and lack of accurate regional information, this study aimed to investigate the developmental disorders and related factors in low weight infants. Methods: This retrospective cohort study was performed on 76, 4-12 month-old infants with a history of hospitalization in NICU of Shiraz Hazrat Zeinab Hospital with an average weight of 1800 grams. These infants were evaluated developmentally by ASQ (Age and stage questionnaire). The data was analyzed by statistical tests. Results: Using ASQ , 17% of children were detected as having developmental disorders. The percentages of developmental disorders for fine and gross motor domains, problem solving ability, communication and personal-social behaviors were 14.5%, 23.7%, 19.7%, 17.6% and 14.5%, respectively. The correlation coefficient statistical test did not show any significant relationship between developmental disorder with mechanical ventilation, duration of hospitalization, surfactant and betamethasone injection, and final diagnosis of diseases (r < 1). Conclusions: Although improvement in respiratory therapy, monitoring system, non-invasive procedures and developmental care have decreased neonatal mortality rate and prematurity complications, but we cannot find any relationship between related risk factors and neurological outcomes. Developmental delay of low birth weight infants must be detected and rehabilitation started soon after discharge from NICU.
Background: The neonatal period or the first 28 days after birth is a critical and vulnerable time for a child period, and the mortality rate is high due to the severe problems which might happen during this period. The goal of this study was to compare the risk factors associated with the neonatal mortality rate (NMR) before and after the implementation of the health sector evolution plan (HSEP) in Fars Province, Iran.
Methods: This study was a retrospective cross-sectional study. This research was conducted using the census method, and 275951 newborns’ files were studied. Variables are expressed as percentage and frequency. The chi-square test and Fisher tests was used to measure the significance level of variables. A multivariate logistic regression model was also used to estimate the odds ratio of neonatal mortality and risk factors associated with neonatal mortality. All statistical tests were performed bilaterally with P-value < 0.05 considered as significant. All tests were conducted using the software SPSS19.
Results: After HSEP, risk factors of pregnancy and delivery complications were significantly reduced, and abnormalities were significantly increased (P-value < 0.001). Using multivariate logistic regression analysis, the risk of death is nine times more in gestational age below 37 weeks compared to gestational age over 37 weeks. The chances of neonatal mortality among neonates weighing less than 1000 grams are much more, and it is about 140 times more than normal weight (over 2500 grams). There was not a significant relationship between the chance of neonatal mortality and the implementation of HSEP (P-value > 0.05).
Conclusion: Neonates with abnormal weight and premature neonates had the highest chance of death. Therefore, the prevention of preterm labor and low-birth-weight infants are essential factors in reducing neonatal mortality. This study suggests that improved health service quality is determinative to decrease neonatal mortality rate.
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