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Color centers are versatile systems that generate quantum light, sense magnetic fields and produce spin‐photon entanglement. We review how these properties have pushed the limits of fundamental knowledge in a variety of scientific disciplines, from rejecting local‐realistic theories to sensing superconducting phase transitions. In the light of recent progress in material processing and device fabrication, we identify new opportunities for interdisciplinary fundamental discoveries in physics and geochemistry.

A Ti 3 (Al x Cu 1-x )C 2 phase with Cu atoms with a degree of ordering in the A plane is synthesized through A-site-replacement reaction in CuCl 2 molten salt. The weakly bonded single-atom-thick Cu layers in Ti 3 (Al x Cu 1-x )C 2 MAX phase provide actives sites for catalysis chemistry. As-synthesized Ti 3 (Al x Cu 1-x )C 2 presents unusual peroxidase-like catalytic activity similar to natural enzymes. A fabricated Ti 3 (Al x Cu 1x )C 2 /chitosan/Glassy carbon electrodes (GCE) biosensor prototype also exhibits a low detection limit in electrochemical sensing of H 2 O 2 . These results have broad implications for property tailoring in nanolaminated MAX phase by replacing the A

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