A practical and scalable protocol for electrochemical arylation of quinoxalin(on)es with arylhydrazine hydrochlorides under mild conditions has been developed. This method exhibits high efficiency, easy scalability, and broad functional group tolerance. Various quinoxalin(on)es and arylhydrazines underwent this transformation smoothly in an undivided cell, providing the corresponding aryl-substituted quinoxalin(on)es in moderate to good yields. A radical mechanism is involved in this arylation reaction.
Visible light-driven self-catalyzed regulable alkylation of 2H-benzothiazoles with diverse aliphatic C–H donors via the combination of HAT and self-photoredox catalysis.
A general and facile approach for the direct oxidative α-acyloxylation of ketones using molecular oxygen as the oxidant is developed. This method avoids the use of excessive peroxides and expensive metal catalysts, affording a variety of αacyloxylated ketones in satisfactory yields. Experimental studies indicate that the reaction proceeds via a radical pathway. Additionally, α-hydroxy ketones could be obtained by changing the solvent.
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