Objectives: The prevalence of hypertension, diabetes mellitus, dyslipidemia, and obesity in developing countries was high regardless the socioeconomicstatus, whereas the awareness and the control of these metabolic disorders were inadequate. The aim was to compare the cardiovascular risk basedon numbers of metabolic disorders among lower socioeconomic subjects.Methods: The study was done with the analytical cross-sectional method. The subjects were selected with cluster random sampling from four villages.We included the subjects of 30-65 years old and signed the informed consent but excluded the subjects who had not fasted for 8-10 hrs. We analyzedthe cardiovascular parameters among groups with ANOVA statistics, the difference between actual and heart vascular age (HVA) with paired t-test,and the change of six cardiovascular parameters with radar diagram.Results: The eligible subjects (n=222) comprised 0-4 metabolic disorders at 25.2%, 33.8%, 28.8%, 9.9%, and 1.8%, respectively; with age at50.1±9.0 years; body mass index (BMI) 24.1±4.8 kg/m2; blood pressure (BP) 141.6±23.4/82.8±11.7 mmHg; fasting blood sugar (FBS) 98.7±37.4 mg/dL;total and high-density lipoprotein cholesterol 201.0±37.9 and 55.1±12.7 mg/dL; Framingham score was 11.4±8.9% (referred as medium risk); thedifference between actual and HVA at 13.2±13.0 (p<0.05). Increasing metabolic disorders lead to higher BP, FBS, cholesterol, Framingham score, andthe difference between actual and HVA (p<0.05) excluding BMI in the four metabolic disorder subgroup.Conclusion: The subjects had the medium cardiovascular risk with above normal BMI, BP, and total cholesterol profiles. The average age, BP, FBS,cholesterol, Framingham score, and HVA were likely to increase equivalent to the numbers of metabolic disorders.Keywords: Hypertension, Diabetes mellitus, Dyslipidemia, Obesity, Cardiovascular risk, Metabolic disorders.
AbstrakSindrom metabolik (SM) merupakan salah satu faktor risiko penyakit kardiovaskular (PKV). Gaya hidup tidak sehat cenderung meningkatkan kejadian SM dan PKV. Masyarakat pedesaan mempunyai akses sumber informasi tentang gaya hidup sehat yang relatif terbatas. Oleh karena itu, penelitian ini bertujuan mengeksplorasi hubungan antara pengetahuan, sikap, dan tindakan (PST) terkait gaya hidup sehat dengan risiko PKV di kalangan masyarakat pedesaan di D.I. Yogyakarta. Jenis penelitian ini adalah observasional analitik dengan desain potong lintang. Sampel penelitian direkrut secara non-random purposive di dua dusun yaitu Tanjung dan Dlingseng, Desa Banjaroyo, Kecamatan Kalibawang, Kabupaten Kulonprogo, D.I. Yogyakarta. Kriteria inklusi responden yaitu penduduk dewasa sehat berusia 30-75 tahun. Kriteria eksklusi yaitu wanita hamil dan responden yang datanya tidak lengkap. Data dikumpulkan pada Bulan Mei-Juni 2018. Data pengetahuan, sikap, dan tindakan terkait gaya hidup sehat (PST) dikumpulkan menggunakan kuesioner. Data faktor risiko PKV yaitu indeks massa tubuh (IMT), lingkar pinggang (LP), tekanan darah (TD), kadar gula darah puasa (GDP), dan kolesterol total (Chol) diperoleh melalui pengukuran. Data dianalisis secara deskriptif korelatif dengan Spearman correlation. Sebanyak 124 data responden dianalisis. Sebanyak 56,5% responden mempunyai tingkat pengetahuan tinggi, 66,1% sikap positif, dan 67,7% melakukan tindakan hidup sehat. Sebanyak 55,6% IMT responden termasuk obes general; 65% ukuran LP wanita dan 25% LP pria termasuk obes sentral; median TD sistol di atas normal dan diastol normal; median GDP dan kolesterol normal. Hasil yang diharapkan adalah PST dan faktor risiko PKV berkorelasi negatif. Namun, hasil analisis menunjukkan beberapa faktor risiko PKV berkorelasi positif dengan PST. Hal ini kemungkinan disebabkan oleh faktor social desirability bias, the phenomenon of intention not translated into action, dan recall bias pada pengukuran pengetahuan, sikap, dan tindakan. AbstractMetabolic syndrome (MS) is one of risk factors of cardiovascular disease (CVD). Unhealthy lifestyle tends to elevate the risk of MS. People in rural area might not have adequate access to information on healthy lifestyle. Hence, this study aimed to explore association between knowledge, attitude, and practices (KAP) on healthy lifestyle and cardiovascular (CVD) risk factors among rural adults in Yogyakarta Province. This is an observational analytic study with cross sectional design. Samples were recruited purposively in two sub-villages, i.e.: Tanjung and Dlingseng in Banjaroyo, Kalibawang, Kulonprogo. Inclusion criteria were healthy adult people in between 30 to 75 years old. Those who were pregnant and those who did not complete the data were excluded. Data collection was conducted during May to June 2018. Data on KAP were gathered using a questionnaire. Data on CVD risk factors were collected through measurements of body mass index (BMI), waist circumference (WC), blood pressure (BP), fasting blood glucose (FBG), and total choles...
EFEK PEMBERIAN JUS BUAH PISANG AMBON (Musa 15, 20, 45, 60, 90, 120, 180, and 240
Kejadian sindrom metabolik (SM) dan penyakit kardiovaskular (PKV) dipengaruhi oleh gaya hidup sehat sehari-hari. Penelitian ini bertujuan mengeksplorasi profil gaya hidup sehat dan pengetahuan tentang hidup sehat dengan pemberian intervensi edukasi di kalangan masyarakat pedesaan di D.I. Yogyakarta. Penelitian ini bersifat eksperimental semu dengan desain potong lintang. Variabel yang diteliti adalah profil gaya hidup sehat dan pengetahuan tentang gaya hidup sehat sebelum dan setelah edukasi tentang gaya hidup sehat. Sampel penelitian dipilih secara non-random purposive dengan kriteria inklusi yaitu penduduk dewasa sehat, di dua dusun yaitu Tanjung dan Dlingseng, Desa Banjaroyo, Kecamatan Kalibawang, Kabupaten Kulonprogo, D.I. Yogyakarta. Data dikumpulkan pada bulan Juli-Agustus 2019 dengan kuesioner yang telah diujicoba, kemudian dianalisis secara deskriptif dan komparatif. Sebanyak 108 responden berpartisipasi dalam penelitian ini. Sebagian besar responden merupakan perempuan (63,9%), median usia 54 tahun (rentang: 27-76 tahun), dan memiliki tingkat pendidikan tergolong rendah (82,4%). Profil gaya hidup sehat secara umum baik, yaitu lebih dari 50% responden tidak merokok, aktif secara fisik, tidak minum alkohol, menu harian rendah glukosa, rendah kolesterol, dan tinggi serat sayur dan buah. Sebanyak 64,1% responden mempunyai tingkat pengetahuan tentang gaya hidup sehat pada kategori tinggi. Namun, variabel tingkat pengetahuan tidak berasosiasi dengan semua variabel profil gaya hidup sehat, kecuali variabel aktivitas fisik. Edukasi mampu meningkatkan pengetahuan secara signifikan dengan rata-rata skor sebelum edukasi 7,0, setelah edukasi 8,0, dan satu bulan setelah edukasi 9,0 (p=0,000). Edukasi penting dilakukan untuk menjamin keberlanjutan gaya hidup sehat tersebut.
Hepatoprotective effect study of forest honey had been conducted on a female rat induced with carbon tetrachloride (CCl4). The study aimed at obtaining the scientific data and the evidence of forest honey as hepatoprotective agent on the rat. The study was a true experimental study with a single factor completely randomized design. Thirty rats were randomly divided into six groups (n=5). Group I received carbon tetrachloride 2.0 mL/kgBW intraperitoneally, group II received olive oil 2.0 mL/kgBW intraperitoneally, group III received forest honey 8.1 mL/kgBW (6 days, peroral), groups IV, V, VI were given forest honey 3.6, 5.4, 8.1 mL/kgBW (6 days, peroral) and intraperitoneal induction of carbon tetrachloride 2 mL/kgBW on seventh day. The blood sample of all rats were taken for ALT-AST measurement and their liver were sampled for histological examination of the liver cell. Groups I and III on the seventh day, group II on the second day, groups IV,V,VI on the eighth day. The result showed that a forest honey can be used as a hepatoprotective agent on the female rat Wistar strain induced by carbon tetrachloride 2 mL/kgBW with doses 3.6, 5.4, 8.1 mL/kgBW. Keywords: ALT-AST, carbon tetrachloride, forest honey, liver histopathology 3,6; 5,4; 8,1 mL/kgBB (6 hari, p.o) 3,6; 5,4; dan 8,1 mL/kgBB. ABSTRAK Telah dilakukan penelitian efek hepatoprotektif madu hutan pada tikus betina terinduksi karbon tetraklorida (CCl4) dengan tujuan membuktikan efek hepatoprotektif madu hutan pada tikus galur wistar yang diinduksi karbon tetraklorida. Jenis penelitian ini adalah eksperimental murni dengan rancangan acak lengkap pola searah. Tiga puluh ekor tikus dibagi secara acak ke dalam enam kelompok (n=5). Kelompok I diberi karbon tetraklorida 2,0 mL/kgBB secara intraperitoneal (i.p). Kelompok II diberi olive oil 2,0 mL/kg BB secara i.p. Kelompok III diberi madu hutan 8,1 mL/kgBB (6 hari, peroral (p.o)); kelompok IV, V, VI diberi madu hutan
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