With the development of the times and the progress of society, the scientific and cultural achievements of human beings are constantly accumulated, and a large number of science and technology are widely used in people’s daily production and life. Under the background of the current big data era, China’s economic system reform of all walks of life is in full swing, and the economic system and structure of all walks of life are gradually improving. The teaching reform of Applied Economics in Colleges and universities in China also needs to follow the trend of the times. Nowadays, the knowledge structure required by students majoring in Applied Economics in Colleges and universities has also changed greatly compared with the past. In order to cope with this change, this paper puts forward the method of integrating big data technology with the teaching reform of Applied Economics in Colleges and universities, and carries out the current situation of the teaching of Applied Economics in Colleges and universities In order to meet the new needs of applied economics students in the new era, this paper analyzes and combines the new requirements of the era of big data for students majoring in Applied Economics. Through long-term research, we can find that some analysis methods proposed in this paper have important practical significance for the application of big data technology in the teaching reform of Applied Economics in Colleges and universities.
Under the background of the current big data era, all walks of life in China are carrying out reform and innovation on their operating mechanism, so as to better cope with the challenges brought by the new era. The research of financial abnormal transaction model in China’s securities market also needs to follow the development trend of the times. Compared with the past, great changes have taken place in the research of financial abnormal transaction model in the securities market. In order to meet the challenges brought by the new era to the research of financial abnormal transaction model of securities market, this paper puts forward the application of big data technology to the financial abnormal transaction model of securities market This paper analyzes the research status of financial abnormal transaction model in China’s securities market, and formulates a new research scheme for financial abnormal transaction model of securities market in the era of big data, so as to meet the new needs of the research on financial abnormal transaction model of China’s securities market in the new era Please. Through long-term observation, it can be found that some of the analysis methods proposed in this paper have important practical significance for the research of abnormal trading model of securities market based on big data technology.
BackgroundTreatment of growth hormone disorders typically involves daily injections of human growth hormone (GH) over many years, incurring substantial costs. We assessed the extent of undesired GH loss due to leakage in the course of pen preparation prior to injection, and differences between the prescribed dose, based on patient weight, and the actual delivered dose based on pen dosing increments in five GH administration devices.MethodsNorditropin® prefilled FlexPro®, NordiFlex®, NordiLet®, and durable NordiPen®/SimpleXx® 5 mg pens (Novo Nordisk A/S, Bagsværd, Denmark) and durable Omnitrope® Pen-5 devices (Sandoz, Holzkirchen, Germany) were tested (n = 40 for each device type). Product wastage was measured in accordance with validated protocols in an ISO (International Organization for Standardization) 11608-1 and Good Manufacturing Practice compliant laboratory. The average mass of wasted GH from each device type was measured in simulations of dripping with the needle attached prior to injection and while setting a dose. Statistical significance (P < 0.05) was confirmed by Student’s t-test, and a model was constructed to estimate mean annual GH wastage per patient in cohorts of pediatric patients with GH disorders.ResultsMean GH mass wasted with the needle on prior to injection was 0.0 μg with Norditropin pens, relative to 98 μg with Omnitrope Pen-5. During dose dialing, 0.0–2.3 μg of GH was lost with Norditropin pens versus 0.8 μg with Omnitrope Pen-5. All Norditropin and Omnitrope device comparisons were statistically significant. Modeling GH wastage in a US cohort showed 5.5 mg of annual GH wastage per patient with FlexPro versus 43.6 mg with Omnitrope, corresponding to 7–8 additional pens per patient annually.ConclusionOverall, Norditropin pens resulted in significantly less wastage than the Omnitrope Pen-5. The study suggests that GH devices of the same nominal volume exhibit differences that may affect the frequency of GH prescription refills required to remain adherent to therapy.
quality of life using the EQ-5D collected in the SWISSspine registry. METHODS: The analysis was based on the SWISSspine registry, covering BKP treatment of 1027 fractured vertebrae in 765 patients with osteoporosis, trauma and cancer, from 2005-2011 in Switzerland. In the registry, data is collected before operation and at follow-ups at 3-6 months, 1 year and annually thereafter. The health-dimensional contribution to the overall quality of life improvements was analysed by isolating the impact of each dimension on quality of life based on the EQ-5D. It was assumed that the change in QoL over one year was solely due to treatment received. RESULTS: Mean age was 70.4 years and 70.1% of the patients were women. The mean accumulated QoL improvement compared to pre-surgery over one year was 0.40, 0.46 and 0.38 for osteoporotic, trauma and cancer patients, respectively. Changes in pain, as measured by EQ-5D, explained 45% of the QoL change for osteoporotic patients, 40% for patients with cancer and 35% for patients who suffered trauma. Mobility and self-care were the second and third most important dimensions respectively, varying between 19 -29% for all indications. Improvement in usual activities contributed 9 -14% to improvement in quality of life and anxiety 2-7%. CONCLUSIONS: Changes in the pain dimension of health are the most important driver for overall quality of life in patients treated with BKP. However, ignoring the impact of mobility and self-care would lead to an underestimation of the actual improvement in overall quality of life.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.