PMD81 Evaluation of Product Wastage From Modern Human Growth Hormone Administration Devices

Abstract

quality of life using the EQ-5D collected in the SWISSspine registry. METHODS: The analysis was based on the SWISSspine registry, covering BKP treatment of 1027 fractured vertebrae in 765 patients with osteoporosis, trauma and cancer, from 2005-2011 in Switzerland. In the registry, data is collected before operation and at follow-ups at 3-6 months, 1 year and annually thereafter. The health-dimensional contribution to the overall quality of life improvements was analysed by isolating the impact of each dimension on quality of life based on the EQ-5D. It was assumed that the change in QoL over one year was solely due to treatment received. RESULTS: Mean age was 70.4 years and 70.1% of the patients were women. The mean accumulated QoL improvement compared to pre-surgery over one year was 0.40, 0.46 and 0.38 for osteoporotic, trauma and cancer patients, respectively. Changes in pain, as measured by EQ-5D, explained 45% of the QoL change for osteoporotic patients, 40% for patients with cancer and 35% for patients who suffered trauma. Mobility and self-care were the second and third most important dimensions respectively, varying between 19 -29% for all indications. Improvement in usual activities contributed 9 -14% to improvement in quality of life and anxiety 2-7%. CONCLUSIONS: Changes in the pain dimension of health are the most important driver for overall quality of life in patients treated with BKP. However, ignoring the impact of mobility and self-care would lead to an underestimation of the actual improvement in overall quality of life.