Main observation and conclusion
Boswelliains A—E (1—5), five new cembrane‐type diterpenoids, were isolated from the resin of Boswellia papyifera. Their structures, determined by using spectroscopic, computational and chemical methods, demonstrate that 2—5 are novel 4,5‐seco‐, 4,5‐seco‐, 9,10‐seco‐, and 6,7‐seco‐cembrane diterpenoids, and that 1, 4 and 5 bear aldehyde moieties. An evaluation of the wound healing properties of these natural products along with a derivative of 2 shows that compounds 2 and 3 significantly stimulate proliferation, mobility and tuber formation of human umbilical vein endothelial cells (HUVECs) at the concentration of 20 μmol/L.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.