Calix [n]arenes are a class of macrocycles that have attracted much interest because of their potential for forming host-guest complexes, and have been extensively investigated in various fields. In this study, in an attempt to develop calix[n]arenes as an effective analytical reagent with enzyme-like activity, the peroxidase-like activity of the ion-exchangers modified with some metal complexes of thiacalix[4]arenetetrasulfonate (Fig. 1) was investigated. The modified ion-exchanger with the highest activity was applied for the determination of hydrogen peroxide and glucose in place of peroxidase.
Calix [n]arenes are of much interest because of their high selectivity and specificity for forming host-guest complexes. 2,3 In analytical chemistry, various calix[n]arene derivatives have been developed by modifying either the upper or lower rim in order to apply them as analytical reagents for separations 4-7 and sensors 8-12 of various ions, molecules, and so on. It has been shown that recently developed thiacalix[n]arenes have a very interesting characteristic: an ability to form very stable metal complexes without modifying the upper and/or lower rims. 13
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.