Brachytherapy using 198Au grains is minimally invasive and the only curative treatment for early tongue cancer in patients of advanced age or poor performance status available in our institution. From March 1993 to February 2008, 198Au grains were used to treat a group of 96 Stage I–II tongue cancer patients who could not undergo surgery or brachytherapy using 192Ir pins because of an advanced age (≥75 years) or poor performance status (≥2). The patients were followed for 3.9 ± 3.3 years, and the cause-specific survival and local control rates were determined. Survival analyses were performed using the Kaplan-Meier method, and univariate and multivariate analyses were performed using the Cox proportional hazard model. The results were compared with those for a group of 193 early tongue-cancer patients who underwent treatment using iridium pins. The 5-year cause-specific survival and local control rates of the 198Au grains group were 71% and 68%, respectively, both of which were 16% lower than the corresponding rates for the 192Ir pins group. Our study demonstrated that as the last curative treatment available, 198Au grain implantation could be used to achieve moderate treatment results for early tongue cancer in patients of advanced age or poor performance status.
The SUV(max) was significantly higher and the CT density was significantly lower in PTL as compared with those in chronic thyroiditis. Thus, (18)F-FDG PET/CT may be useful for distinguishing between PTL and chronic thyroiditis.
Our data demonstrated the longitudinal progressions of vascular inflammation and calcification of health-screening subjects. Inflammation and calcification were observed to progress significantly faster in the abdominal aorta than in the thoracic aorta. The progressions of vascular inflammation and calcification may be associated with different atherogenic risk factors.
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