The associations between sarcopenia and metabolic syndrome (MetS) in non-obese middle-aged and older adults remain controversial. Thus, this meta-analysis aimed to evaluate the overall prevalence of MetS and the correlations between sarcopenia and MetS in middle-aged and older non-obese adults. We performed a systematic searched strategy using PUBMED, EMBASE and Web of Science databases for relevant observational studies investigating sarcopenia and MetS up to 11 May 2017. The polled prevalence of MetS and odds ratios with 95% confidence intervals (CI), as well as subgroup analyses were calculated using a random effects model. Twelve articles with a total of 35,581 participants were included. The overall prevalence of MetS was 36.45% (95% CI, 28.28–45.48%) in middle-aged and older non-obese adults with sarcopenia. Our analysis demonstrated a positive association between sarcopenia and MetS (OR = 2.01, 95% CI, 1.63–2.47). The subgroup analysis showed that both larger cohort size and the use of dual-energy X-ray absorptiometry to measure body composition can enhance the relationship. Our study revealed that a higher proportion of MetS in middle-aged and older non-obese people with sarcopenia. Moreover, sarcopenia was positively associated with MetS in this population. Further large-scale prospective cohort studies are needed to investigate the causality between sarcopenia and MetS.
This study aimed to evaluate the associations of nighttime sleep duration and midday napping with risk of depressive symptoms incidence and persistence among middle-aged and older Chinese. Data from China Health and Retirement Longitudinal Study, CHARLS (2011–2013), were analyzed. Depressive symptoms were identified by the 10-item version of the Centre for Epidemiological Studies Depression scale (CESD-10). Multivariate binary logistic regression models were fitted. There were 7156 individuals with CESD-10 scores < 10 and 3896 individuals with CESD-10 scores ≥ 10 at baseline included in this study. After controlling for potential covariates, nighttime sleep duration <6 hours was associated with high risk of incident depressive symptoms (OR = 1.450, 95%CI: 1.193, 1.764 for middle aged population, and OR = 2.084, 95%CI:1.479, 2.936 for elderly) and persistent depressive symptoms (OR = 1.404, 95%CI: 1.161, 1.699 for middle aged population, and OR = 1.365, 95%CI: 0.979, 1.904 for elderly). For depressed individuals, longer midday napping (≥60 minutes) was associated with lower persistent depressive symptoms (OR = 0.842, 95%CI: 0.717, 0.989). Our study concluded that short nighttime sleep duration was an independent risk factor of depressive symptoms incidence and persistence. Depressed individuals with long midday napping were more likely to achieve reversion than those who have no siesta habit.
Limits to flight performance at high altitude potentially reflect variable constraints deriving from the simultaneous challenges of hypobaric, hypodense and cold air. Differences in flight-related morphology and maximum lifting capacity have been well characterized for different hummingbird species across elevational gradients, but relevant within-species variation has not yet been identified in any bird species. Here we evaluate load-lifting capacity for Eurasian tree sparrow (Passer montanus) populations at three different elevations in China, and correlate maximum lifted loads with relevant anatomical features including wing shape, wing size, and heart and lung masses. Sparrows were heavier and possessed more rounded and longer wings at higher elevations; relative heart and lung masses were also greater with altitude, although relative flight muscle mass remained constant. By contrast, maximum lifting capacity relative to body weight declined over the same elevational range, while the effective wing loading in flight (i.e. the ratio of body weight and maximum lifted weight to total wing area) remained constant, suggesting aerodynamic constraints on performance in parallel with enhanced heart and lung masses to offset hypoxic challenge. Mechanical limits to take-off performance may thus be exacerbated at higher elevations, which may in turn result in behavioral differences in escape responses among populations.
Current evidence on the relationship between dietary fiber intake and risk of hyperuricemia is limited.
Higher baseline UA level was associated with better cognition in later life but not with rates of cognitive decline among middle-aged and older Chinese.
Background: Bringing free-living animals into captivity subjects them to the stress of both capture and captivity, leading to the alteration of normal physiological processes and behaviors through activation of the hypothalamicpituitary-adrenal axis. In free-living birds, although elevated plasma corticosterone (CORT) is an important adaptation regulating physiological and behavioral responses during the process of capture and captivity stress, little information is currently available on the effects of such stress on plasma metabolite levels. Methods:We examined the effects of immediate capture and 24-h captivity on body mass, body condition, plasma CORT, and metabolite levels including glucose (Glu), triglyceride (TG), total cholesterol (TC), uric acid (UA), in breeding Eurasian Tree Sparrows (Passer montanus).Results: CORT and Glu levels were increased significantly by the stress of capture, whereas TC and UA levels decreased. Body mass, body condition declined notably after 24 h in captivity, but CORT, Glu, and UA levels increased. Furthermore, male sparrows had lower TG levels after both capture and captivity than those of females. The relationships between plasma CORT and metabolite levels varied between sexes. Conclusions:Our results revealed that the metabolic status of Eurasian Tree Sparrows could be dramatically altered by capture and captivity. Monitoring the dynamic effects of both capture and captivity on plasma CORT, metabolite levels in a free-living bird contributes to a better understanding of the stress-induced pathways involved in sexdependent energy mobilization.
Physical stimuli from contacted objects are recorded by skin receptors and are transmitted to neural signals to the cerebrum to generate touch perceptions. Despite numerous studies having been conducted on the link between the physical properties of contacted objects and psychological sensations, factors besides the stimuli themselves have seldom been investigated. The contact method and acclimation to environmental factors, such as temperature and humidity, could affect the functions of responsible receptors, which, in consequence, might affect the touch perception. This study is designed around a series of experiments involving 226 human subjects adapted to the climate environments of six East-Asia cities. The results revealed that the contact method affected the responses of smoothness sensation but not the stimuli discriminations. This agrees with the hypothesis that both the slowly adapting type I (SA1) fiber and the Pacinian afferent (PC) fiber are responsible for smoothness sensation. SA1 fibers can function through passive touch because of a superficial location in the dermis, while PC fibers, which are located deeper in the dermis, are triggered during active touching. The effect of contact method on softness sensation is not significant because the responsible receptor is the SA1 fiber. The effects of acclimation to temperature and relative humidity were also investigated. Positive relationships were found with smoothness perception and negative relationships were found with warmth perception. This suggests that acclimation to temperature and relative humidity can affect the receptor thresholds and, in consequence, affect the touch sensation.
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