Background
The Gram-negative bacterium
Kerstersia gyiorum
, a potential etiological agent of clinical infections, was isolated from several human patients presenting clinical symptoms. Its significance as a possible pathogen has been previously overlooked as no disease has thus far been definitively associated with this bacterium. To better understand how the organism contributes to the infectious disease, we determined the complete genomic sequence of
K
.
gyiorum
SWMUKG01, the first clinical isolate from southwest China.
Results
The genomic data obtained displayed a single circular chromosome of 3, 945, 801 base pairs in length, which contains 3, 441 protein-coding genes, 55 tRNA genes and 9 rRNA genes. Analysis on the full spectrum of protein coding genes for cellular structures, two-component regulatory systems and iron uptake pathways that may be important for the success of the bacterial survival, colonization and establishment in the host conferred new insights into the virulence characteristics of
K
.
gyiorum
. Phylogenomic comparisons with
Alcaligenaceae
species indicated that
K
.
gyiorum
SWMUKG01 had a close evolutionary relationships with
Alcaligenes aquatilis
and
Alcaligenes faecalis
.
Conclusions
The comprehensive analysis presented in this work determinates for the first time a complete genome sequence of
K
.
gyiorum
, which is expected to provide useful information for subsequent studies on pathogenesis of this species.
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